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Journals / Düzce Tıp Fakültesi Dergisi / 2025 / Volume: 27 Issue: 3

Oral Focal Mucinosis of the Edentulous Area of the Maxilla: A Rare Case Report

Maksillanın Dişsiz Bölgesinde Oral Fokal Müsinozis: Nadir Bir Olgu Sunumu

Shubhangi Mani(Rural Dental College, Loni (Mharashtra) India)0009-0008-4160-6857
Deepak Singh(Rural Dental College, Loni)0000-0002-5841-1764
Manas Bajpai(RURAL DENTAL COLLEGE (PIMS -DU))0000-0001-6168-3069
Pages
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Publication Date
2025-12-25
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case highlights the importance of considering OFM in the differential diagnosis of soft tissue lesions of the oral cavity, even in edentulous patients, and underscores the diagnostic role of histopathology.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Oral focal mucinosis (OFM) is a relatively uncommon benign connective tissue lesion of unknown etiology, primarily affecting the gingiva.
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Key Findings & Data:This case report aimed to describe clinical, histological, and immunohistochemical features of an OFM in a 71-year-old edentulous male patient affecting the right maxillary alveolar mucosa.
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Conclusion & Impact:This case highlights the importance of considering OFM in the differential diagnosis of soft tissue lesions of the oral cavity, even in edentulous patients, and underscores the diagnostic role of histopathology.
🔬Design:Case Report
📍Scope:Comprehensive Sample
⚙️Variables:Oral focal mucinosis · myxoid lesion · oral pathology

Abstract

Oral focal mucinosis (OFM) is a relatively uncommon benign connective tissue lesion of unknown etiology, primarily affecting the gingiva. Clinically, OFM has no specific appearance; it resembles more specific conditions like fibroepithelial hyperplasia and other reactive lesions. Histologically, it is characterized by loose myxoid connective tissue stroma with slightly enlarged fibroblasts. This case report aimed to describe clinical, histological, and immunohistochemical features of an OFM in a 71-year-old edentulous male patient affecting the right maxillary alveolar mucosa. The lesion presented as a painless, dome-shaped, sessile nodule. Histopathological examination revealed a circumscribed area of increased mucin deposition within the lamina propria, devoid of inflammatory cells. This case highlights the importance of considering OFM in the differential diagnosis of soft tissue lesions of the oral cavity, even in edentulous patients, and underscores the diagnostic role of histopathology.

Özet

Oral fokal müsinozis (OFM), etiyolojisi bilinmeyen, nispeten nadir görülen iyi huylu bir bağ dokusu lezyonudur ve öncelikli olarak dişetini etkiler. Klinik olarak OFM'nin spesifik bir görünümü yoktur; fibroepitelyal hiperplazi ve diğer reaktif lezyonlar gibi daha spesifik durumlara benzerlik gösterebilir. Histolojik olarak, hafif büyümüş fibroblastlar içeren gevşek miksoid bağ dokusu stroması ile karakterizedir. Bu olgu sunumunun amacı, 71 yaşında dişsiz bir erkek hastada sağ maksiller alveolar mukozayı etkileyen bir OFM'nin klinik, histolojik ve immünohistokimyasal özelliklerini tanımlamaktır. Lezyon ağrısız, kubbemsi şekilde, sesil bir nodül olarak izlenmiştir. Histopatolojik incelemede, lamina propriada inflamatuvar hücre içermeyen, sınırlı bir alanda artmış müsin birikimi gözlenmiştir. Bu olgu, oral kavite yumuşak doku lezyonlarının ayırıcı tanısında, dişsiz hastalarda dahi, OFM’nin göz önünde bulundurulması gerektiğinin öneminin altını çizmekte ve histopatolojinin tanıdaki rolünü vurgulamaktadır.

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Cite This Article

Mani, S., Singh, D., Bajpai, M. (2025). Oral Focal Mucinosis of the Edentulous Area of the Maxilla: A Rare Case Report. Düzce Tıp Fakültesi Dergisi, Volume: 27 Issue: 3. https://doi.org/10.18678/dtfd.1685751

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