Journals / The Turkish Journal of Ear Nose and Throat / 2026 / Volume: 11 Issue: 5

Kimura's disease in the parotid and submandibular regions: two case reports

Parotis ve submandibüler bölgede Kimura hastalığı: İki olgu sunumu

Selma Kurukahvecioğlu(SSK Ankara Eğitim Hastanesi 2. Kulak Burun Boğaz Hastalıkları Kliniği)
Sumru Yardımcı(SSK Ankara Eğitim Hastanesi 2. Kulak Burun Boğaz Hastalıkları Kliniği)
Osman Kurukahvecioğlu(Gazi Üniversitesi Tıp Fakültesi Genel Cerrahi Anabilim Dalı, Ankara.)
Erdal Yılmaz(Gazi Üniversitesi Tıp Fakültesi Genel Cerrahi Anabilim Dalı, Ankara.)
Pages
—
Publication Date
2003-10-13
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Postoperatively, no recurrences were detected within a year follow-up.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Two male patients aged 13 and 50 years who pre- sented with a complaint of painless mass in the parotid and submandibular regions, respectively, were found to have eosinophilia and increased blood immunoglobulin E IgE levels.
📊
Key Findings & Data:Following ultrasonographic examination of the masses, surgical excision was performed.
💡
Conclusion & Impact:Postoperatively, no recurrences were detected within a year follow-up.
🔬Design:Article
📍Scope:Comprehensive Sample
⚙️Variables:Angiolymphoid hyperplasia with eosinophilia/ pathology/surgery · parotid gland/pathology · submandibu­lar gland

Abstract

Two male patients aged 13 and 50 years who pre- sented with a complaint of painless mass in the parotid and submandibular regions, respectively, were found to have eosinophilia and increased blood immunoglobulin E IgE levels. Following ultrasonographic examination of the masses, surgical excision was performed. Histopathologic evaluation revealed massive lymphocytic and eosinophilic infiltration.Histopathologic findings and the presence of peripheral eosinophilia and high IgE levels led to a diagnosis of Kimura’s disease. Postoperatively, no recurrences were detected within a year follow-up.

Özet

Biri parotis bölgesinde diğeri submandibüler bölge- de olmak üzere ağrısız kitle flikayetiyle baflvuran 13 ve 50 yafllarındaki iki erkek hastanın kanında eozinofili ve yüksek immünglobulin E IgE düzeyi saptandı. Kitle varlığı ultrasonografi ile de belirlen- dikten sonra lezyonlar cerrahi eksizyonla çıkarıldı. Histopatolojik incelemede örneklerde yoğun lenfo- sitik ve eozinofilik infiltrasyon görüldü. Periferal eo- zinofili, yüksek IgE düzeyi ve histopatolojik bulgular ıflığında olgulara Kimura hastalığı tanısı kondu. Cerrahi tedaviden sonra iki hasta da birer yıl izlen- di ve nüks görülmedi

🔖

Cite This Article

Kurukahvecioğlu, S., Yardımcı, S., Kurukahvecioğlu, O., Yılmaz, E. (2003). Kimura's disease in the parotid and submandibular regions: two case reports. The Turkish Journal of Ear Nose and Throat, Volume: 11 Issue: 5. https://ajindex.com/articles/1330159

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Pamaraju N, Khalifa SA, Darwish A, Paulose KO, Ahmed N, Yousif H. Kimura’s disease. J Laryngol Otol 1996;110:1084-7.
  2. Kaneko K, Aoki M, Hattori S, Sato M, Kawana S. Successful treatment of Kimura’s disease with cyclosporine. J Am Acad Dermatol 1999;41(5 Pt 2):893-4.
  3. Armstrong WB, Allison G, Pena F, Kim JK. Kimura’s disease: two case reports and a literature review. Ann Otol Rhinol Laryngol 1998;107:1066-71.
  4. Terada N, Konno A, Shirotori K, Fujisawa T, Atsuta J, Ichimi R, et al. Mechanism of eosinophil infiltration in the patient with subcutaneous angioblastic lymphoid hyperplasia with eosinophilia (Kimura’s disease). Mechanism of eosinophil chemotaxis mediated by Candida antigen and IL-5. Int Arch Allergy Immunol 1994;104(Suppl 1):18-20.
  5. Takenaka T, Okuda M, Usami A, Kawabori S, Ogami Y. Histological and immunological studies on eosinophilic granuloma of soft tissue, so-called Kimura’s disease. Clin Allergy 1976;6:27-39.
  6. Tabata H, Ishikawa O, Ohnishi K, Ishikawa H. Kimura’s disease with marked proliferation of HLA- DR+CD4+ T cells in the skin, lymph node and periph- eral blood. Dermatology 1992;184:145-8.
  7. Olsen TG, Helwig EB. Angiolymphoid hyperplasia with eosinophilia. A clinicopathologic study of 116 patients. J Am Acad Dermatol 1985;12(5 Pt 1):781-96.
  8. Chusid MJ, Rock AL, Sty JR, Oechler HW, Beste DJ. Kimura’s disease: an unusual cause of cervical tumour. Arch Dis Child 1997;77:153-4.
  9. Som PM, Biller HF. Kimura disease involving parotid gland and cervical nodes: CT and MR findings. J Comput Assist Tomogr 1992;16:320-2.
  10. Gumbs MA, Pai NB, Saraiya RJ, Rubinstein J, Vythilingam L, Choi YJ. Kimura’s disease: a case re p o r t and literature re v i e w. J Surg Oncol 1999;70:190-3.
  11. Kennedy SM, Pitts JF, Lee WR, Gibbons DC. Bilateral Kimura’s disease of the eyelids. Br J Ophthalmol 1992; 76:755-7.
  12. Karavattathayyil SJ, Krause JR. Kimura’s disease: a case report. Ear Nose Throat J 2000;79:195-6, 199.
  13. Mariatos G, Gorgoulis VG, Laskaris G, Kittas C. Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia) in the oral mucosa. A case report and review of the literature. Oral Oncol 1999;35:435-8.