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Journals / The Turkish Journal of Ear Nose and Throat / 2020 / Volume: 30 Issue: 4

The effect of vitamin D levels on prognosis of patients with facial paralysis

Ayşe Enise Göker(Department of Otorhinolaryngology, Okmeydanı Training and Research Hospital, Istanbul Turkey)
Semih Karaketir(Department of Otorhinolaryngology, Bulanık State Hospital, Muş, Turkey)
Maide Hacer Alagöz(Department of Biochemistry, Department Okmeydanı Training and Research Hospital, Istanbul Turkey)
Ayca Başkadem Yılmazer(Department of Otorhinolaryngology, Okmeydanı Training and Research Hospital, Istanbul Turkey)
Hüseyin Sarı(Department of Otorhinolaryngology, Okmeydanı Training and Research Hospital, Istanbul Turkey)
Hasan Sami Bircan(Department of Otorhinolaryngology, Okmeydanı Training and Research Hospital, Istanbul Turkey)
Nilgün Başaran(Department of Biochemistry, Department Okmeydanı Training and Research Hospital, Istanbul Turkey)
Pages
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Publication Date
2020-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Our study results indicate that vitamin D deficiency can affect prognosis of BP patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: This study aims to investigate the serum 25-hydroxyvitamin D3 [25 OH D3] levels of patients with Bell’s palsy BP , and to evaluate their role in prognosis and their impact on the disease etiology.
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Key Findings & Data:Patients and Methods: A total of 49 patients 30 males, 19 females; mean age: 42.2±13.6 years; range, 19 to 67 years who were diagnosed with BP and treated at our clinic between October 2019 and April 2020 were included.
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Conclusion & Impact:Conclusion: Our study results indicate that vitamin D deficiency can affect prognosis of BP patients.
🔬Design:Article
📍Scope:2019 Verileri
⚙️Variables:Bell’s palsy · facial paralysis · vitamin D deficiency

Abstract

Objectives: This study aims to investigate the serum 25-hydroxyvitamin D3 [25 OH D3] levels of patients with Bell’s palsy BP , and to evaluate their role in prognosis and their impact on the disease etiology. Patients and Methods: A total of 49 patients 30 males, 19 females; mean age: 42.2±13.6 years; range, 19 to 67 years who were diagnosed with BP and treated at our clinic between October 2019 and April 2020 were included. Blood samples were collected within 24 h after the onset of BP symptoms, and a standard oral pharmacological treatment was administered with prednisolone 1 mg/kg for 10 days and acyclovir 700 mg/day for six days. All patients were graded according to the House-Brackmann scale HBS . The patients were divided into three groups as Grade 2, Grade 3, Grade ≥4. The patients with BP were further divided into two groups as healed n=36 and not-healed ones n=13 . The vitamin D levels of the groups were compared. Results: Eleven 22% patients were in the Grade 2 group, 21 43% patients were in the Grade 3 group, and 17 35% patients were in the Grade ≥4 group. A significant decrease in vitamin D levels was observed in the patients with HBS Grade ≥4, compared to Grade 3 and Grade 2 groups p=0.002 and p<0.001, respectively . Vitamin D levels were significantly higher among the patients without sequelae than those with sequelae p<0.001 . Conclusion: Our study results indicate that vitamin D deficiency can affect prognosis of BP patients.

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Cite This Article

Göker, A. E., Karaketir, S., Alagöz, M. H., Yılmazer, A. B., Sarı, H., Bircan, H. S., Başaran, N. (2020). The effect of vitamin D levels on prognosis of patients with facial paralysis. The Turkish Journal of Ear Nose and Throat, Volume: 30 Issue: 4. https://ajindex.com/articles/1329266

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