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Journals / The Turkish Journal of Ear Nose and Throat / 2026 / Volume: 35 Issue: 2

Evaluation of Fine Needle Aspiration Biopsy and Histopathology Results in Salivary Gland Masses

Yunus Kantekin(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0003-4332-725X
Nuri Ünsal(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0002-5247-5345
Esra Dişbudak(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0003-0141-8233
Serap Bulut Çöbden(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0002-4471-1934
Altan Kaya(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0001-8918-9054
Mehmet Yaşar(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0002-8246-6853
Ali Bayram(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0002-0061-1755
İbrahim Özcan(Kayseri City Training and Research Hospital, Clinic of Ear Nose and Throat)0000-0002-4359-2988
Hatice Karaman(Kayseri City Training and Research Hospital, Clinic of Patology)0000-0002-5250-5663
Pages
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Publication Date
2025-06-11
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results demonstrate that the accuracy of FNAB varies depending on the pathologist’s experience and the quality of sampling.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to compare the Fine Needle Aspiration Biopsy (FNAB) results with histopathological outcomes in salivary gland masses and to determine the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FNAB.
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Key Findings & Data:Methods: The study included 103 patients who underwent surgery for salivary gland masses between 2019 and 2022.
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Conclusion & Impact:The results demonstrate that the accuracy of FNAB varies depending on the pathologist’s experience and the quality of sampling.
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Biopsy · Needle · Parotid Gland

Abstract

Objective: The aim of this study was to compare the Fine Needle Aspiration Biopsy (FNAB) results with histopathological outcomes in salivary gland masses and to determine the sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of FNAB. Methods: The study included 103 patients who underwent surgery for salivary gland masses between 2019 and 2022. FNAB was performed under ultrasound guidance, and the samples were examined. Preoperative FNAB results were classified as benign, malignant, or nondiagnostic and compared with the postoperative histopathological results. Results: Of the patients included in the study, 48 (46.6%) were female and 55 (53.4%) were male. The most frequent FNAB was performed on the parotid gland, and histopathological results were reported as benign in 89 patients and malignant in 14 patients. The sensitivity of FNAB was found to be 80%, specificity 100%, positive predictive value 100%, and negative predictive value 97%. The nondiagnostic result rate was 6.8%. Conclusion: FNAB is a safe, rapid, and cost-effective method for diagnosing salivary gland masses. The study demonstrates that FNAB provides high accuracy in the early detection of malignant tumours. However, false-negative results may occur in low-grade malignant tumours. The results demonstrate that the accuracy of FNAB varies depending on the pathologist’s experience and the quality of sampling.

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Cite This Article

Kantekin, Y., Ünsal, N., Dişbudak, E., Çöbden, S. B., Kaya, A., Yaşar, M., Bayram, A., Özcan, İ., Karaman, H. (2025). Evaluation of Fine Needle Aspiration Biopsy and Histopathology Results in Salivary Gland Masses. The Turkish Journal of Ear Nose and Throat, Volume: 35 Issue: 2. https://doi.org/10.26650/Tr-ENT.2025.1611147

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