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Journals / Turkish Journal of Clinics and Laboratory / 2026 / Cilt: 9 Sayı: 2

The effect of nutritional support treatment on growth factors in adolescents with nutritional short stature: result of long-term follow-up

Nutrisyonel boy kısalığı olan adolesanlarda nutrisyonel destek tedavisinin büyüme faktörleri üzerine etkisi: uzun süreli izlem sonuçları

Ayça Törel Ergür(KIRIKKALE UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, PEDIATRIC ENDOCRINOLOGY)
Fatma Nişancı Kılınç(KIRIKKALE UNIVERSITY, FACULTY OF HEALTH SCIENCES, DEPARTMENT OF NUTRITION AND DIETETICS)
Sevinç Odabaşı Güneş(KIRIKKALE UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, PEDIATRIC ENDOCRINOLOGY)
Çağlar Yörgüç(KIRIKKALE UNIVERSITY, FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CHILD HEALTH AND DISEASES, PEDIATRIC ENDOCRINOLOGY)
Üçler Kısa(Department of Biochemistry, Kırıkkale University Faculty of Medicine, Kırıkkale)
Pages
126–130
Publication Date
2018-09-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The increment of IGF-1 levels was in between secure limits.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Long-term insufficient nutrition intake in childhood affects height gain negatively.
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Key Findings & Data:Effect of nutritional support treatment on GV, GF and growth parameters were analyzed on 0 th , 6 th , 12 th months.
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Conclusion & Impact:The increment of IGF-1 levels was in between secure limits.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Nutrisyon tedavisi · boy kısalığı · adolesan

Abstract

Aim: Long-term insufficient nutrition intake in childhood affects height gain negatively. This study was designed to analyze the effect of oral nutritional support product (ONSP) treatment on growth velocity (GV) and growth factors (GF) in adolescents who diagnosed as nutritional short stature (NSS). Material and Methods : Sixteen adolescents diagnosed as NSS were involved. Patients recorded their dietary intake; caloric deficiencies were calculated and fulfilled with ONSP. Effect of nutritional support treatment on GV, GF and growth parameters were analyzed on 0 th , 6 th , 12 th months. Results: T he increment of the height of the cases on 6 th and 12 th month, increment of IGFBP3 on 6 th month, the increment of IGF-1 levels, BMI and weight SDS of the cases on 12 th month and were statistically significant (p < 0.05). Conclusions: Long-term ONSP treatment, which is given to the adolescents with NSS increases the growth factors. The increment of IGF-1 levels was in between secure limits.

Özet

Amaç: Uzun süreli yetersiz nutrisyon alımı çocukluk çağında boy kazanımını negatif olarak etkiler. Bu çalışmanın amacı nutrisyonel boy kısalığı (NBK) tanısı alan adolesanlarda oral nutrisyonel destek ürününün (ONDÜ) büyüme hızı (BH) ve büyüme faktörleri (BF) üzerine olan etkisini incelemektir. Gereç ve Yöntemler : NBK tanısı alan 16 adolesan çalışmaya dahil edildi. Hastalar oral beslenme ile alımlarını kaydetti, kalori açıkları hesaplandı ve açıkları ONDÜ ile tamamlandı. Nutrisyonel destek tedavisinin BH, BF ve büyüme parametreleri üzerine etkisi 0, 6, 12. aylarda değerlendirildi. Bulgular: Olguların 6. ve 12. aylardaki boy kazanımları; 6. aydaki IGF-BP3 artışı; 12. aydaki IGF-1, beden kitle indeksi ve vücut ağırlığı SDS artışı istatistiksel olarak anlanlı saptandı. (p<0.05). Sonuç: Nutrisyonel boy kısalığı olan adolesanlara verilen uzun sureli ONDÜ tedavisi büyüme faktörlerini arttırmaktadır. IGF-1 seviyesindeki artış güvenli sınırlar içerisinde saptanmıştır.

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Cite This Article

Ergür, A. T., Kılınç, F. N., Güneş, S. O., Yörgüç, Ç., Kısa, Ü. (2018). The effect of nutritional support treatment on growth factors in adolescents with nutritional short stature: result of long-term follow-up. Turkish Journal of Clinics and Laboratory, Cilt: 9 Sayı: 2, 126–130. https://doi.org/10.18663/tjcl.320100

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