SavedAdd your journal

Journals / Zeynep Kamil Tıp Bülteni / 2026 / Cilt: 41 Sayı: 2

Atypical colonization in cystic fibrosis

Kistik fibroziste atipik kolonizasyon

Rabia Gönül Sezer
ÖZAHİ İlke İpek
Abdulkadir Bozaykut
Lale Pulat Seren
Cem Paketçi
ASYA İlhan Tanju
Pages
99–102
Publication Date
2010-03-01
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Antibiotic treatment targetting these new colonizations, in addition to the primary colonizing pathogens, may improve the management of infective exacerbations of cystic fibrosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Chronic bacterial colonization is the leading cause of morbidity and mortality in patients with cystic fibrosis.
📊
Key Findings & Data:Case Report: Deep tracheal aspiration cultures of a-4-months old boy with cystic fibrosis revealed Enterobacteria, Metisillin Sensitive Staphylococcus aerius and E.coli with 1 week intervals.
💡
Conclusion & Impact:Conclusion: Antibiotic treatment targetting these new colonizations, in addition to the primary colonizing pathogens, may improve the management of infective exacerbations of cystic fibrosis.
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Chronic bacterial colonization is the leading cause of morbidity and mortality in patients with cystic fibrosis. Case Report: Deep tracheal aspiration cultures of a-4-months old boy with cystic fibrosis revealed Enterobacteria, Metisillin Sensitive Staphylococcus aerius and E.coli with 1 week intervals. He was treated with gentamicin, sefuroxime axetil, cefoperazone respectively. All these results were taken as atypical colonizations in our patient. Conclusion: Antibiotic treatment targetting these new colonizations, in addition to the primary colonizing pathogens, may improve the management of infective exacerbations of cystic fibrosis.

Özet

Giriş: Kronik bakteriyeî havayolu kolonizasyonları kistik fibrozis hastalarındaki mortalite ve morbiditenin ana sebeplerindendir. Olgu Sunumu: Kistik fibrosis tanısı konulan 4 aylık erkek hastanın birer hafta ara ile alınan derin trakeal aspirasyon kültürlerinde Enterobacteria, Metisilline hassas Staphylococcus aerius ve 2 kez E.coli üremesi saptandı. Hastaya sırasıyla gentamisin, sefuroksim aksetti ve sefoperazon tedavileri verildi. Hastadaki bu üremeler atipik kolonizasyon olarak değerlendirildi. Sonuç: Enfeksiyon tedavisi gereken kistik fibrozis hastalarına antibiyotik tedavisi planlanırken yeni bildirilen kolonizasyonlar da göz önünde bulundurulmalıdır.

🔖

Cite This Article

Sezer, R. G., İpek, Ö. İ., Bozaykut, A., Seren, L. P., Paketçi, C., Tanju, A. İ. (2010). Atypical colonization in cystic fibrosis. Zeynep Kamil Tıp Bülteni, Cilt: 41 Sayı: 2, 99–102. https://doi.org/10.16948/zktb.74246

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Çetin İ. Kistik fibroziste solunum sistemi belirtileri. Katkı Pediatri Dergisi 2002;23(2):150-6
  2. Field TR, Sibley CD, Parkins MD, Rabin HR, Surette MG. The genus Prevotella in cystic fibrosis airways. Anaerobe 2010; 20. [Epub ahead of print] 3- George AM, Jones PM, Middleton PG. Cystic fibrosis infections: treatment strategies and prospects. FEMS Microbiol Lett 2009;300(2):153-64
  3. Hill RL, Kearns AM, Nash J et al.Linezolid-resistant ST36 methicillin-resistant Staphylococcus. aureus associated with prolonged linezolid treatment in two paediatric cystic fibrosis patients. J Antimicrob Chemother 2010;65(3):442-5
  4. Tunney MM, Field TR, Moriarty TF et al. Detection of anaerobic bacteria in high numbers in sputum from patients with cystic fibrosis. Am J Respir Crit Care Med 2008;177(9):995-1001
  5. Chotirmall SH, O'Donoghue E, Bennett K, Gunaratnam C, O'Neill S J, McElvaney NG. Sputum Candida Albicans presages FEV1 decline and hospitalized exacerbations in cystic fibrosis. Chest 2010. [Epub ahead of print] 7- Giraud S, Pihet M, Razafimandimby B et al. Geosmithia argillacea: an emerging pathogen in cystic fibrosis patients ? J Clin Microbiol 2010. [Epub ahead of print] 8-Hatziagorou E, Walsh TJ, Tsanakas JN, Roilides E. Aspergillus and the paediatric lung. Paediatr Respir Rev 2009;10(4):178-85
  6. Griffard E A, Guajardo JR, Cooperstock MS, Scoville CL. Isolation of Exophiala dermatitidis from pigmented sputum in a cystic fibrosis patient. Pediatr Pulmonol 2010;45(5):508-10
  7. Bittar F, Stremler N, Audie JP et al. Nocardia farcinica lung infection in a patient with cystic fibrosis: a case report. J Med Case Reports 2010;8(4):84
  8. Beucher J, Belleguic C, Brinchault G, Deneuville E, Donnio PY, Roussey M. Nocardia farcinica infection in a patient with cystic fibrosis. Rev Mai Respir 2010;27(l):76-9
  9. SmithJJ, Travis SM, GreenbergEP, Welsh MJ. Cystic Fibrosis Airway Epithelia Fail to Kill Bacteria Because of Abnormal Airway Surface Fluid. Cell 1996;85(2):229-36