Journals / Online Türk Sağlık Bilimleri Dergisi / 2026 / Cilt: 6 Sayı: 2

Does Phototherapy Influence Alpha Melanocyte Stimulating Hormone Levels?

Fototerapi Alfa Melanosit Uyarıcı Hormon Seviyelerini Etkiler mi?

Meltem Karabay(SAKARYA UNIVERSITY, SAKARYA HEALTH ACADEMY)0000-0001-7105-7176
Erdem Çokluk(SAKARYA ÜNV TIP FAKÜLTESİ)0000-0002-6205-5109
Pages
201–206
Publication Date
2021-06-05
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: This study demonstrated that there was no effect between phototherapy applied for newborn IHB and plasma α-MSH levels.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to investigate the effect of phototherapy on plasma alpha-melanocyte-stimulating hormone (α-MSH) levels of newborns with indirect hyperbilirubinemia (IHB) for the first time.
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Key Findings & Data:Materials and Methods: A total of 45 cases, who were hospitalized in neonatal intensive care units between July 1, 2019, to September 30, 2019, and received phototherapy, were retrospectively included in the study.
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Conclusion & Impact:Conclusion: This study demonstrated that there was no effect between phototherapy applied for newborn IHB and plasma α-MSH levels.
🔬Design:Araştırma Makalesi
📍Scope:2019 Verileri
⚙️Variables:Alfa-melanosit uyarıcı hormon · indirekt hiperbilirubinemi · fototerapi

Abstract

Objective: We aimed to investigate the effect of phototherapy on plasma alpha-melanocyte-stimulating hormone (α-MSH) levels of newborns with indirect hyperbilirubinemia (IHB) for the first time. Materials and Methods: A total of 45 cases, who were hospitalized in neonatal intensive care units between July 1, 2019, to September 30, 2019, and received phototherapy, were retrospectively included in the study. Plasma α-MSH and bilirubin levels were measured before and after the phototherapy. Results: A total of 45 newborns (19 girls and 26 boys) were included in to study. The average birth weight was 3202 grams and the mean total bilirubin level was 17.2 mg/dL. α-MSH levels before and after phototherapy were 326.2 (4.0-2228.0) ng/L and 373.9 (8.7-2283.0) ng/L, respectively and did not represent a significant difference (p>0.05). Conclusion: This study demonstrated that there was no effect between phototherapy applied for newborn IHB and plasma α-MSH levels.

Özet

Amaç: İlk kez bu araştırmayla indirekt hiperbilirubinemi (İHB) olan yenidoğanlarda fototerapinin plazma alfa-melanosit uyarıcı hormon (α-MSH) üzerine etkisinin araştırılması amaçlanmıştır. Materyal ve Metot: İHB nedeniyle yenidoğan yoğun bakım ünitesinde yatarak fototerapi tedavisi uygulanan 45 olgu, 1 Temmuz 2019-30 Eylül 2019 tarihleri arasında prospektif olarak çalışmaya dahil edildi. Fototerapi öncesi ve sonrası plazma α-MSH ve bilirubin düzeyleri ölçüldü. Bulgular: Çalışmaya 45 yenidoğan (19 kız, 26 erkek) dahil edildi. Ortalama doğum kilosu 3202 gr ve ortalama total bilirubin düzeyi 17,2 mg /dl idi. Fototerapi öncesi ve sonrası α-MSH seviyeleri sırasıyla 326,2 (4,0-2228,0) ng/L ve 373,9 (8,7-2283,0) ng/L olup benzerdi (p> 0,05). Sonuç: Bu çalışmayla İHB için yenidoğanlara uygulanan fototerapinin, plazma α-MSH üzerine etkisi olmadığı saptanmıştır.

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Cite This Article

Karabay, M., Çokluk, E. (2021). Does Phototherapy Influence Alpha Melanocyte Stimulating Hormone Levels?. Online Türk Sağlık Bilimleri Dergisi, Cilt: 6 Sayı: 2, 201–206. https://doi.org/10.26453/otjhs.881968

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