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Journals / Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi / 2026 / Volume: 12 Issue: 2

The Role of Coronary Computed Tomography Angiography in Detecting Coronary Artery Stenosis

Koroner Arter Darlıklarının Saptanmasında Koroner Bilgisayarlı Tomografi Anjiyografinin Rolü

Halil Serdar Aslan(PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-5255-8618
Çetin Çelenk0000-0002-6078-7525
Kadir Han Alver(PAMUKKALE ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-4692-2401
Pages
—
Publication Date
2025-08-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results demonstrate that Coronary Computed Tomography Angiography, as supported by the literature, is a promising alternative method for detecting coronary artery stenosis.

📌 3 Key Takeaways

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Objective & Hypothesis:The aim of this study is to evaluate the role of Coronary Computed Tomography Angiography, a minimally invasive imaging method, in detecting coronary artery stenosis.
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Key Findings & Data:This study retrospectively analyzed the coronary artery segments of 66 patients who underwent both Conventional Coronary Angiography and Coronary Computed Tomography Angiography at Ondokuz Mayıs University Hospital between May 2005 and November 2007.
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Conclusion & Impact:These results demonstrate that Coronary Computed Tomography Angiography, as supported by the literature, is a promising alternative method for detecting coronary artery stenosis.
🔬Design:Research Article
📍Scope:2005 Verileri
⚙️Variables:Stenosis · Conventional Coronary Angiography · Coronary Computed Tomography Angiography

Abstract

The aim of this study is to evaluate the role of Coronary Computed Tomography Angiography, a minimally invasive imaging method, in detecting coronary artery stenosis. This study retrospectively analyzed the coronary artery segments of 66 patients who underwent both Conventional Coronary Angiography and Coronary Computed Tomography Angiography at Ondokuz Mayıs University Hospital between May 2005 and November 2007. These patients were referred with indications such as angina pectoris, stent evaluation, or suspected coronary artery disease. Coronary artery segments were categorized into proximal, mid, and distal groups using the classification system defined by the American Heart Association. The degree of stenosis was evaluated based on the following classification: mild (1–49%), significant (50–74%), advanced (75–99%), and total occlusion (100%). The data obtained from Coronary Computed Tomography Angiography were retrospectively compared with the findings from Conventional Coronary Angiography. According to these findings, the sensitivity and specificity of Coronary Computed Tomography Angiography across all groups were calculated as 87% and 97%, respectively. Atherosclerotic changes in proximal segments led to a decrease in specificity, while difficulties in assessing distal segments resulted in reduced sensitivity. These results demonstrate that Coronary Computed Tomography Angiography, as supported by the literature, is a promising alternative method for detecting coronary artery stenosis. With advancements in technology, it is poised to become an effective tool for diagnosing coronary artery disease, which is rapidly increasing in prevalence in industrialized societies, and for screening asymptomatic patients who are at risk.

Özet

Bu çalışmanın amacı koroner arter darlıklarının saptanmasında minimal invaziv bir görüntüleme yöntemi olan Koroner Bilgisayarlı Tomografi Anjiografi’nin rolünü değerlendirmektir. Çalışma Mayıs 2005 ve Kasım 2007 tarihleri arasında Ondokuz Mayıs Üniversitesi Hastanesinde Anjina pektoris, stent kontrolü, koroner arter hastalığı şüphesi olan hem Konvansiyonel Koroner Anjiografi hem de Koroner Bilgisayarlı Tomografi Anjiografi yapılmış 66 hastanın koroner arter segmentleri darlık yönünden retrospektif değerlendirmeye alındı. Koroner Bilgisayarlı Tomografi Anjiografi ile koroner arter segmentleri American Heart Association sınıflaması kullanılarak proksimal, orta ve distal gruplara ayrıldı. Darlık düzeyleri hafif (%1-49), anlamlı (%50-74), ileri (%75-99) ve oklüzyon (%100) sınıflaması ile değerlendirildi. Elde edilen veriler Konvansiyonel Koroner Anjiografi sonuçları ile retrospektif olarak karşılaştırıldı. Bu verilere göre tüm gruplarda Koroner Bilgisayarlı Tomografi Anjiografi’nin duyarlılığı %87, özgüllüğü %97 olarak hesaplanmıştır. Proksimal segmentlerdeki aterosklerotik değişiklikler özgüllüğün azalması, distal segmentlerin değerlendirilmesindeki güçlük ise duyarlılığın azalması olarak yansımıştır. Bu bulgularla; koroner arter darlıklarının saptanmasında, yapılan çalışmalarda desteklemekte ki Koroner Bilgisayarlı Tomografi Anjiografi, gelişen teknoloji ile birlikte, endüstriyel toplumlarda yaygınlığı hızla artan koroner arter hastalıkları tanısında ve risk altındaki asemptomatik hastaların taranmasında alternatif bir yöntem olmaya adaydır.

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Cite This Article

Aslan, H. S., Çelenk, Ç., Alver, K. H. (2025). The Role of Coronary Computed Tomography Angiography in Detecting Coronary Artery Stenosis. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, Volume: 12 Issue: 2. https://doi.org/10.47572/muskutd.1605140

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References (28)

  1. Boersma E, Mercado N, Poldermans D et al. Acute myocardial infarction. Lancet. 2003;361:847–58.
  2. Reeder GS, Gersh BJ Modern management of acute myocardial infarction. Curr. Probl. Cardiol. 2000;25:677–782.
  3. Worthley SG, Farouque HMO, Helft G. et al. Coronary artery imaging in the new millennium. Heart. Lung Circ. 2002;11:19–25.
  4. Popma JJ Coronary Angiography and Intravascular Ultrasound Imaging. Braunwauld’s Heart Disease A Text Book of Cardiology, 7th edn. Elsevier Saunders Philadelphia, pp 423-454, 2005.
  5. Papaconstantinou HD, Marshall AJ, Burrell CJ Diagnostic cardiac catheterisation in a hospital without on-site cardiac surgery. Heart. 1999;81: 465–9.
  6. Sones FMJ, Shirey EK Cine coronary arteriography. Mod. Concepts Cardiovasc. Dis. 1962;31:735–8.
  7. Schoepf UJ, Becker CR, Obuchowski NA et al. Multi-slice computed tomography as a screening tool for colon cancer, lung cancer and coronary artery disease. Eur. Radiol. 2001;11:1975–85.
  8. Knez A, Becke CR, Leber A et al. Usefulness of multislice spiral computed tomography angiography for determination of coronary artery stenoses. Am. J. Cardiol. 2001;88:1191–4.
  9. Nieman K, Cademartiri F, Lemos PA et al. Reliable noninvasive coronary angiography with fast submillimeter multislice spiral computed tomography. Circulation. 2002;106:2051–4.
  10. Nieman K, Rensing BJ, van Geuns R.-J.M. et al. Usefulness of multislice computed tomography for detecting obstructive coronary artery disease. Am. J. Cardiol. 2002;89:913–8.
  11. Pannu HK, Flohr TG, Corl FM et al. Current concepts in multi-detector row CT evaluation of the coronary arteries: principles, techniques, and anatomy. Radiographics. 2003;23;111-25.
  12. Herzog C, Britten M, Balzer JO et al. Multidetector-row cardiac CT: diagnostic value of calcium scoring and CT coronary angiography in patients with symptomatic, but atypical, chest pain. Eur. Radiol. 2004;14:169–77.
  13. Morgan-Hughes GJ, Roobottom CA, Owens PE et al. Highly accurate coronary angiography with submillimetre, 16 slice computed tomography. Heart. 2005;91:308–13.
  14. Kantarci M, Duran C, Durur I et al. Detection of myocardial bridging with ECG-gated MDCT and multiplanar reconstruction. AJR. Am. J. Roentgenol. 2006;186:391-4.
  15. Maron B.J, Thompson PD, Puffer JC et al. Cardiovascular preparticipation screening of competitive athletes. A statement for health professionals from the Sudden Death Committee (clinical cardiology) and Congenital Cardiac Defects Committee (cardiovascular disease in the young). American Heart A, Circulation. 1996;94: 850–6.
  16. Onat A, Keleş İ, Çetinkaya A et al. On yıllık TEKHARF verileri çalışmasına göre Türk erişkinlerinde koroner kökenli ölümlerin prevalansı. Türk Kardiyol. Dern Arş. 2001;29:8–19.
  17. Kantarcı A, Duran C, Durur I et al. Koroner arterlerin değerlendirilmesinde multi dedektör BT anjiyografi: teknik, anatomi ve varyasyonlar. Bilgi. tomografi bülteni. 2005;8:89–98.
  18. Fuchs T, Kachelriess M, Kalender W.A. Technical advances in multi-slice spiral CT. Eur. J. Radiol. 2000;36:69–73.
  19. Kato Y, Nair S, Sano H et al. Multi-slice 3D-CTA - an improvement over single slice helical CTA for cerebral aneurysms. Acta Neurochir. 2002;144:715–22.
  20. Nieman K, Rensing BJ, van Geuns RJM et al. Non-invasive coronary angiography with multislice spiral computed tomography: impact of heart rate. Heart. 2002;88:470–4.
  21. Nieman K, Oudkerk M, Rensing BJ et al. Coronary angiography with multi-slice computed tomography. Lancet. 2001;357:599–603.
  22. Achenbach S, Giesler T, Ropers D et al. Detection of coronary artery stenoses by contrast-enhanced, retrospectively electrocardiographically-gated, multislice spiral computed tomography. Circulation. 2001;103:2535–8.
  23. Ropers D, Baum U, Pohle K et al. Detection of coronary artery stenoses with thin-slice multi-detector row spiral computed tomography and multiplanar reconstruction. Circulation. 2003;107:664–6.
  24. Aviram G, Finkelstein A, I Herz et al. Clinical value of 16-slice multi-detector CT compared to invasive coronary angiography. Int. J. Cardiovasc. Intervent. 2005;7:21–8.
  25. Kuettner A, Kopp AF, S Schroeder et al. Diagnostic accuracy of multidetector computed tomography coronary angiography in patients with angiographically proven coronary artery disease. J Am Coll Cardiol. 2004;43:831–9.
  26. Heuschmid M, Kuettner A, Schroeder S et al. ECG-gated 16-MDCT of the coronary arteries: assessment of image quality and accuracy in detecting stenoses. AJR. Am. J. Roentgenol. 2005;184:1413–9.
  27. Ngam PI, Ong CC, Chai P et al. Computed tomography coronary angiography - past, present and future. Singapore Med. J. 2020;61:109–15.
  28. Abbara S, Shaw LJ Past, Present, and Future of CTA. Circulation. 2024;150:87–90.