Journals / Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi / 2026 / Volume: 12 Issue: 2

Investigation of the Clinical Features and Long-Term Functional Status of Patients with a Diagnosis of Covid-19 Followed in the Intensive Care Unit

Yoğun Bakım Ünitesinde Takip Edilen Covid-19 Tanılı Hastaların Klinik Özelliklerinin ve Taburculuk Sonrası Uzun Dönem Fonksiyonel Durumlarının İncelenmesi

Emrah Harman(UNIVERSITY OF HEALTH SCIENCES, HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES)0000-0002-1554-0419
Dursun Elmas(UNIVERSITY OF HEALTH SCIENCES, HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES)0000-0002-3452-529X
Muhammet Cemal Kızılarslanoğlu(UNIVERSITY OF HEALTH SCIENCES, HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES)0000-0002-7632-6811
Pages
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Publication Date
2025-08-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Furthermore, patients who could be discharged may experience a deterioration in their life activities, nutritional status, and physical performance for months compared to their condition before COVID-19 infection.

📌 3 Key Takeaways

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Objective & Hypothesis:The study aims to examine the clinical features and mortality-related factors of COVID-19 patients in critical condition and their long-term functional status in survivors.
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Key Findings & Data:All COVID-19 patients admitted to our intensive care unit (ICU) between March 2020 and November 2020 were included in the study.
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Conclusion & Impact:Furthermore, patients who could be discharged may experience a deterioration in their life activities, nutritional status, and physical performance for months compared to their condition before COVID-19 infection.
🔬Design:Modeling & Simulation
📍Scope:2020 Verileri
⚙️Variables:COVID-19 · Length of Stay · Intensive Care Unit

Abstract

The study aims to examine the clinical features and mortality-related factors of COVID-19 patients in critical condition and their long-term functional status in survivors. All COVID-19 patients admitted to our intensive care unit (ICU) between March 2020 and November 2020 were included in the study. In the ICU, mortality-related parameters were evaluated using univariate and multiple analyses. The long-term functional status of daily living activities (Katz ADL and Lawton IADL), nutrition (MNA-SF), frailty (FRAIL index), and life satisfaction tests were evaluated by assessing the final status at home after discharge in critically ill COVID-19 patients. A total of 203 COVID-19 patients were included in the study (55.2% male, median age 76 years, median ICU stay 7 days, APACHE II score median 19 points, and mortality rate 81.8%). Invasive mechanical ventilation use was found to be an independent risk factor for ICU mortality in multiple regression models. Twenty-two (22/203, 11.0%) patients were evaluated by telephoneregarding their functional status. Median follow-up times after discharge were 169 days (97-324). The Katz ADL, Lawton IADL, MNA-SF, FRAIL index, and Life Satisfaction Scale scores were worse than before COVID-19 infection. In this study, it has been shown that mortality rates may be high, and invasive mechanical ventilation support was an independent risk factor for mortality in patients hospitalized in the intensive care unit due to COVID-19, especially in the early stages of the pandemic. Furthermore, patients who could be discharged may experience a deterioration in their life activities, nutritional status, and physical performance for months compared to their condition before COVID-19 infection.

Özet

Çalışma, kritik durumdaki COVID-19 hastalarının klinik özelliklerini, mortalite ile ilişkili faktörlerini ve hayatta kalanlarda uzun vadeli fonksiyonel durumlarını incelemeyi amaçlamaktadır. Mart 2020 ile Kasım 2020 tarihleri arasında yoğun bakım ünitemize başvuran tüm COVID-19 hastaları çalışmaya dahil edilmiştir. Mortalite ile ilişkili faktörler, tekli ve çoklu analizlerle incelenmiştir. Günlük yaşam aktiviteleri (Katz ADL ve Lawton IADL), beslenme (MNA-SF), kırılganlık (FRAIL indeksi) ve yaşam memnuniyeti testleri ile değerlendirilen uzun süreli fonksiyonel durumlar, hayatta kalan kritik COVID-19 hastalarında, taburculuk sonrası evdeki son durumları değerlendirilerek incelenmiştir. Çalışmaya toplam 203 COVID-19 hastası dahil edilmiştir (%55.2 erkek, medyan yaş 76 yıl, medyan yoğun bakım kalış süresi 7 gün, APACHE II skoru medyan 19 puan, mortalite oranı %81,8). İnvaziv mekanik ventilasyon gereksiniminin mortalite ile bağımsız ilişkili bir faktör olabileceği, çoklu regresyon analizlerinde gösterilmiştir. Yirmi iki (22/203, %11,0) hasta, telefon görüşmesi ile fonksiyonel durumlarına göre değerlendirilmiştir. Taburculuk sonrası ortanca takip süreleri 169 (97-324) gündü. Katz ADL, Lawton IADL, MNA-SF, FRAIL indeksi ve Yaşam Memnuniyeti Ölçeği puanlarının COVID-19 enfeksiyonundan önceki zamana kıyasla daha kötü olduğu tespit edilmiştir. Bu çalışmada, COVID-19 nedeniyle yoğun bakım ünitesine yatan hastalarda özellikle pandeminin ilk dönemlerinde mortalite oranlarının yüksek olabileceği, invaziv mekanik ventilasyon desteğinin mortalite için bağımsız bir ilişkili faktör olabileceği ve taburcu olabilen hastalarda COVID-19 enfeksiyonu öncesindeki durumlarına kıyasla yaşam aktiviteleri, beslenme durumları ve fiziksel performansları açısından aylarca sürebilen kötüleşme yaşanabileceği gösterilmiştir.

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Cite This Article

Harman, E., Elmas, D., Kızılarslanoğlu, M. C., Harman, S. (2025). Investigation of the Clinical Features and Long-Term Functional Status of Patients with a Diagnosis of Covid-19 Followed in the Intensive Care Unit. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, Volume: 12 Issue: 2. https://doi.org/10.47572/muskutd.1564449

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