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Journals / Meandros Medical And Dental Journal / 2026 / Volume: 23 Issue: 1

Associations Between Glycosylated Hemoglobin (HbA1c) Level and Central Corneal and Macular Thickness in Diabetic Eyes Without Retinopathy

Burcu Kazancı(UNIVERSITY OF HEALTH SCIENCES, INSTITUTE OF HEALTH SCIENCES)
Dilek Özçelik Soba(UNIVERSITY OF HEALTH SCIENCES, INSTITUTE OF HEALTH SCIENCES)
Çağrı İlhan
Yasemin Özdamar Erol(UNIVERSITY OF HEALTH SCIENCES, INSTITUTE OF HEALTH SCIENCES)
Pages
—
Publication Date
2022-03-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This result shown that the macula and corneal thickness cannot be used as indicators of retinopathy and keratopathy.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The comparison of a central corneal (CCT) and central foveal thickness (CMT) of type 2 patients with diabetes with a healthy control group and determine the difference according to fasting blood glucose (FBG), hemoglobin a1c (HbA1c) levels and time of diabetes.
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Key Findings & Data:Materials and Methods: Fifty patients with diabetes without retinopathy and 47 healthy controls of similar age and gender were compared.
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Conclusion & Impact:This result shown that the macula and corneal thickness cannot be used as indicators of retinopathy and keratopathy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Corneal pachymetry · diabetes mellitus · diabetic retinopathy

Abstract

Objective: The comparison of a central corneal (CCT) and central foveal thickness (CMT) of type 2 patients with diabetes with a healthy control group and determine the difference according to fasting blood glucose (FBG), hemoglobin a1c (HbA1c) levels and time of diabetes. Materials and Methods: Fifty patients with diabetes without retinopathy and 47 healthy controls of similar age and gender were compared. The mean of three consecutive corneal thickness measurements at the central cornea was obtained by the Pentacam HR imaging system (Oculus Optikgeräte GmbH, Wetzlar, Germany) and macular thickness was obtained by Heildenberg optical coherence tomography (OCT). The fiber Bragg grating (FBG) and HbA1c levels of all participants were evaluated. The analysis was performed on the right eye. Results: Groups were statistically similar in terms of age and gender (p>0.05). Patients with diabetes had significantly higher FBG and HbA1c values than controls and the percentage of patients with HbA1c values less than 8% in Type 2 diabetes mellitus was significantly lower than healthy controls (p 0.05). Conclusion: In our study, diabetic participants without DR had no difference at CCT and CMT between non-diabetic controls. This result shown that the macula and corneal thickness cannot be used as indicators of retinopathy and keratopathy.

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Cite This Article

Kazancı, B., Soba, D. Ö., İlhan, Ç., Erol, Y. Ö. (2022). Associations Between Glycosylated Hemoglobin (HbA1c) Level and Central Corneal and Macular Thickness in Diabetic Eyes Without Retinopathy. Meandros Medical And Dental Journal, Volume: 23 Issue: 1. https://doi.org/10.4274/meandros.galenos.2021.63626

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