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Journals / Meandros Medical And Dental Journal / 2026 / Volume: 25 Issue: 4

THE UTILITY OF HEMATOLOGICAL INDICES AT THE INITIAL ADMISSION TO THE NEUROSURGERY CLINIC IN CERVICAL DISC HERNIATION

SERVİKAL DİSK HERNİSİNDE NÖROŞİRURJİ KLİNİĞİNE İLK BAŞVURUDA HEMATOLOJİK İNDEKSLERİN YARARI

Havva Yasemin Çinpolat(Department of Medical Biochemistry, Çanakkale Onsekiz Mart University, Faculty of Medicine, Çanakkale, Türkiye)0000-0002-7161-2907
Ali Akar(Department of Neurosurgery, Çanakkale Onsekiz Mart University, Faculty of Medicine, Çanakkale, Türkiye)0000-0002-6567-6218
Ümit Ali Malçok(Department of Neurosurgery, Çanakkale Onsekiz Mart University, Faculty of Medicine, Çanakkale, Türkiye)0000-0002-1272-9654
Sevil Alkan(Department of Infectious Diseases and Clinical Microbiology, Çanakkale Onsekiz Mart University, Faculty of Medicine, Çanakkale, Türkiye)0000-0003-1944-2477
Pages
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Publication Date
2024-12-22
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The observed associations emphasize their practical use in clinical settings, providing the way for further research and their inclusion into routine diagnostic protocols for CDH management.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, it was aimed to investigate the potential of using hematological calculated indices to detect spontaneous regression in cervical disc herniation (CDH) during the initial visit to outpatient clinics.
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Key Findings & Data:Results: Differences in NLR, MLR, and SIII features were statistically significant across groups (p<0.001).
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Conclusion & Impact:The observed associations emphasize their practical use in clinical settings, providing the way for further research and their inclusion into routine diagnostic protocols for CDH management.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:cervical disc herniation · inflammation · systemic immune-inflammatory index

Abstract

Objective: In this study, it was aimed to investigate the potential of using hematological calculated indices to detect spontaneous regression in cervical disc herniation (CDH) during the initial visit to outpatient clinics. Materials and Methods: This retrospective study carried out at a single center reviewed laboratory parameters to assess their significance in the outcomes of CDH. The cohort consisted of patients with CDH who had undergone surgery, those who had undergone conservative treatment and achieved spontaneous regression, and a control group without CDH. The laboratory data consisted of calculated hematological indices such as neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and the systemic immune-inflammatory index (SIII). Results: Differences in NLR, MLR, and SIII features were statistically significant across groups (p<0.001). The surgical intervention group showed significantly higher values of NLR, MLR, and SIII compared to the spontaneous regression and control groups. According to the comparison of the patients with CDH in terms of the level of herniation, there were no significant differences at the C5 and above levels, while there was a statistically significant increase in NLR, MLR, and SIII in the surgical intervention group compared to the spontaneous regression group at the C6-C7 level (p = 0.015, p<0.001, and p = 0.003, respectively). Conclusion: The study provides valuable insights into the use of hematological indices to predict the requirement for surgical intervention in CDH patients. The observed associations emphasize their practical use in clinical settings, providing the way for further research and their inclusion into routine diagnostic protocols for CDH management.

Özet

Amaç: Bu çalışmada, servikal disk hernisi (SDH) olan hastalarda polikliniklere ilk başvuru anında spontan regresyonu öngörmede hematolojik indekslerin araştırılması amaçlandı. Gereç ve Yöntemler: Bu retrospektif çalışma, SDH'nın sonuçlarını değerlendirmek üzere laboratuvar parametrelerinin incelendiği tek bir merkezde gerçekleştirildi. Çalışma grubu, cerrahi müdahale geçiren SDH hastaları, konservatif tedavi görüp spontan regresyon gösteren hastalar ve SDH olmayan kontrol grubundan oluşmuştur. Laboratuvar verileri, nötrofil-lenfosit oranı (NLO), monosit-lenfosit oranı (MLO) ve sistemik immün-enflamatuvar indeksten (SIII) oluşmuştur. Bulgular: NLO, MLO ve SIII değerlerindeki farklılıklar gruplar arasında istatistiksel olarak anlamlı bulunmuştur (p<0.001). Cerrahi müdahale grubu, spontan gerileme gösteren ve kontrol grubuna kıyasla NLO, MLO ve SIII değerlerinde anlamlı derecede daha yüksek sonuçlar göstermiştir. SDH hastaları arasında herniasyon seviyesine göre yapılan karşılaştırmada, C4-C5 ve üzeri seviyelerde anlamlı bir fark bulunmazken, C6-C7 seviyesinde cerrahi müdahale grubunda spontan gerileme grubuna kıyasla NLO, MLO ve SIII değerlerinde istatistiksel olarak anlamlı bir artış gözlenmiştir (sırasıyla p = 0.015, p<0.001 ve p = 0.003). Sonuç: Çalışma, SDH hastalarında cerrahi müdahale gereksinimini öngörmede hematolojik indekslerin kullanımına dair önemli bulgular sunmaktadır. Gözlemlenen bu ilişkiler, hematolojik indekslerin pratik kullanımını vurgulamakta ve SDH yönetiminde rutin tanısal protokollere dahil edilmesine yönelik ileri araştırmaların yolunu açmaktadır.

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Cite This Article

Çinpolat, H. Y., Akar, A., Malçok, Ü. A., Alkan, S., *, H. Y. Ç. (2024). THE UTILITY OF HEMATOLOGICAL INDICES AT THE INITIAL ADMISSION TO THE NEUROSURGERY CLINIC IN CERVICAL DISC HERNIATION. Meandros Medical And Dental Journal, Volume: 25 Issue: 4. https://doi.org/10.69601/meandrosmdj.1559114

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