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Journals / Marmara Medical Journal / 2026 / Volume: 36 Issue: 3

Relationship between COVID-19 and antimicrobial resistance

Tuba Müderris(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI)
Selcuk Kaya(İZMİR KATİP ÇELEBİ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ BÖLÜMÜ, TIBBİ MİKROBİYOLOJİ ANABİLİM DALI)
Fulya Bayındır Bilman(Izmir Katip Celebi University, Ataturk Education and Research Hospital, Department of Medical Microbiology)
Erkan Ozmen(Izmir Katip Celebi University, Ataturk Education and Research Hospital, Department of Medical Microbiology)
Bilal Olcay Peker(Izmir Katip Celebi University, Ataturk Education and Research Hospital, Department of Medical Microbiology)
Ayşegül Aksoy Gökmen(IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF MEDICAL MICROBIOLOGY)
Süreyya Gül Yurtsever(IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF BASIC MEDICAL SCIENCES, DEPARTMENT OF MEDICAL MICROBIOLOGY)
Pages
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Publication Date
2023-09-29
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The data we have presented may help clinicians in the selection of antimicrobials for empirical therapy by revealing the effect of the pandemic on AMR.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Bacterial and fungal infections, antimicrobial resistance (AMR) results of bacterial agents, and the effect of the pandemic on AMR were evaluated in hospitalized COVID-19 patients.
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Key Findings & Data:In addition, the detected AMR rates were compared with the AMR rates of the pre-pandemic period.
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Conclusion & Impact:Conclusion: The data we have presented may help clinicians in the selection of antimicrobials for empirical therapy by revealing the effect of the pandemic on AMR.
🔬Design:Research Article
📍Scope:2020 · 724 samples
⚙️Variables:Antimicrobial resistance · Bacterial infection · COVID-19

Abstract

Objective: Bacterial and fungal infections, antimicrobial resistance (AMR) results of bacterial agents, and the effect of the pandemic on AMR were evaluated in hospitalized COVID-19 patients. In addition, the detected AMR rates were compared with the AMR rates of the pre-pandemic period. Patients and Methods: The isolates grown in respiratory and blood samples of adult patients hospitalized with the diagnosis of COVID-19 between March 2020 and December 2020 were evaluated retrospectively. The same data in hospitalized patients before the pandemic, between March and December 2019, were evaluated retrospectively. Results: A total of 724 samples were included in the study. The superinfection rate was found to be 15.3%. The most frequently isolated microorganisms are; Acinetobacter baumannii (34.4%), Staphylococcus aureus (10.8%), Klebsiella pneumoniae (9.7%) and Pseudomonas aeruginosa (7.3%). The lowest resistance rates in Klebsiella pneumoniae isolates were found for aminoglycosides, in Acinetobacter baumannii isolates were found for trimethoprim-sulfamethoxazole, in Pseudomonas aeruginosa isolates were found for amikacin. When pre-pandemic and pandemic AMR rates were compared; a significant increase in amikacin resistance was detected only in Klebsiella pneumoniae isolates during the pandemic period (P:0.049). Conclusion: The data we have presented may help clinicians in the selection of antimicrobials for empirical therapy by revealing the effect of the pandemic on AMR.

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Cite This Article

Müderris, T., Kaya, S., Bilman, F. B., Ozmen, E., Peker, B. O., Gökmen, A. A., Yurtsever, S. G., *, T. M. (2023). Relationship between COVID-19 and antimicrobial resistance. Marmara Medical Journal, Volume: 36 Issue: 3. https://doi.org/10.5472/marumj.1367895

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