Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine

Objective & Hypothesis:The purpose of the research was to evaluate the genotoxic and anti-genotoxic properties of Schiff bases and their Mn (III) complexes containing L- aspartic acid , and L-phenylalanine .

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Key Findings & Data:The anti-genotoxic properties of four compounds in human lymphocytes cells were investigated by sister chromatid exchanges (SCEs) test system against aflatoxin B 1 (AFB 1 ).

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Conclusion & Impact:The results showed that compounds have strong anti-genotoxic properties.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Aflatoxin Bı · Mn(III) complexes · mutagenicity

Abstract

The purpose of the research was to evaluate the genotoxic and anti-genotoxic properties of Schiff bases and their Mn (III) complexes containing L- aspartic acid , and L-phenylalanine . The anti-genotoxic properties of four compounds in human lymphocytes cells were investigated by sister chromatid exchanges (SCEs) test system against aflatoxin B 1 (AFB 1 ). The results showed that compounds have strong anti-genotoxic properties.

Keywords

Aflatoxin Bı Mn(III) complexes mutagenicity

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Cite This Article

Özkan, E. H., Kızıl, H. E., Şakıyan, İ., Nartop, D., Sarı, N., Ağar, G. (2018). Anti-genotoxic Effects of Schiff bases and their Mn(III) Complexes Containing L-Aspartic acid and L-Phenylalanine. Gazi University Journal of Science, Volume: 31 Issue: 2. https://ajindex.com/articles/1269274

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