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Journals / Gazi University Journal of Science / 2026 / Volume: 38 Issue: 1

The Effects of Anatolian Black Pine Cone Extracts on Carbonic Anhydrase Enzymes

Berfin Vapor(KÜTAHYA DUMLUPINAR ÜNİVERSİTESİ)0009-0006-4878-1661
Ekrem Tunca(Kütahya Dumlupınar Üniversitesi)0000-0001-7556-8379
Pages
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Publication Date
2025-03-01
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It can be said that these results are promising in terms of the potential of Anatolian black pine cone as a natural pharmacological agent.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Nowadays, there is an increasing trend in the use of natural products to treat diseases or alleviate their effects.
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Key Findings & Data:IC50 values were in the range of 5.10 to 49.50 μg/mL for hCA I and 2.57 to 15.07 μg/mL for hCA II.
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Conclusion & Impact:It can be said that these results are promising in terms of the potential of Anatolian black pine cone as a natural pharmacological agent.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Anatolian black pine · Cone · Carbonic anhydrase

Abstract

Nowadays, there is an increasing trend in the use of natural products to treat diseases or alleviate their effects. This situation has emerged as a result of the side effect problem seen in the use of synthetic drugs. In this study, Anatolian black pine cone extracts were prepared using solvents of different polarities (water, methanol, ethanol, ethyl acetate, n-hexane). Then, the effects of these extracts on the esterase activities of hCA I and hCA II isoenzymes, which are associated with many physiological disorders, were examined in vitro. IC50 values were in the range of 5.10 to 49.50 μg/mL for hCA I and 2.57 to 15.07 μg/mL for hCA II. It can be said that these results are promising in terms of the potential of Anatolian black pine cone as a natural pharmacological agent.

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Cite This Article

Vapor, B., Tunca, E., *, E. T. (2025). The Effects of Anatolian Black Pine Cone Extracts on Carbonic Anhydrase Enzymes. Gazi University Journal of Science, Volume: 38 Issue: 1. https://doi.org/10.35378/gujs.1416864

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