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Journals / Kocatepe Veteriner Dergisi / 2021 / Cilt: 14 - Sayı: 1

Effects of Age on The Concentrations of Plasma Cytokines and Lipidperoxidation in Sheep

Koyunlarda Plazma Sitokin ve Lipid Peroksidasyon Düzeylerine Yaşın Etkisi

Mehmet SALİM
İbrahim DURMUŞ
Mehmet BAŞEĞMEZ
İsmail KÜÇÜKKURT
Abdullah ERYAVUZ
Pages
37–44
Publication Date
2021-03-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a result, age has an effect on blood lipid peroxidation and IL-6 levels in sheep.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study is to determine the effects of age on blood cytokine levels and lipid peroxidation product malondialdehyde (MDA) levels and thyroid hormones levels in sheep of different ages.
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Key Findings & Data:Female sheep of lamb (4-6 months), young (12-18 months) and adult (36-40 months) from a herd in same care and feeding conditions were used in the study.
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Conclusion & Impact:As a result, age has an effect on blood lipid peroxidation and IL-6 levels in sheep.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Yaş · koyun · lipid peroksidasyonu

Abstract

The aim of this study is to determine the effects of age on blood cytokine levels and lipid peroxidation product malondialdehyde (MDA) levels and thyroid hormones levels in sheep of different ages. Female sheep of lamb (4-6 months), young (12-18 months) and adult (36-40 months) from a herd in same care and feeding conditions were used in the study. Blood samples were taken before morning feding from 30 sheep in total, 10 heads from each age group. MDA, glutathione (GSH), interleukin-1 (IL-1), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6) and T3 and T4 levels were determined in blood samples. Young animals have significantly higher MDA and lower IL-6 levels than lambs. There was no difference between age groups in terms of GSH, IL-1β, TNF-α, T3 and T4 levels. As a result, age has an effect on blood lipid peroxidation and IL-6 levels in sheep.

Özet

Bu çalışmanın amacı, değişik yaşlardaki koyunlarda kan sitokin düzeyleri ve lipid peroksidasyon ürünü malondialdehid (MDA) seviyesi ile tiroid hormonları düzeylerine yaşın etkilerinin belirlenmesidir. Çalışmada, aynı bakım ve besleme şartlarındaki bir sürüden kuzu (4-6 aylık, kuzu), genç (12-18 aylık) ve ergin (36-40 aylık) dişi koyun kullanıldı. Her bir yaş grubundan 10 baş olmak üzere toplam 30 koyundan sabah yemlemesinden önce kan örnekleri alındı. Kan örneklerinde MDA, glutatyon (GSH), interlökin-1 beta (IL-1β), tümör nekrozis faktör alfa (TNF-α) ve interlökin-6 (IL-6) ile T3 ve T4 düzeyleri belirlendi. Genç koyunların kuzularınkinden önemli oranda daha yüksek plazma MDA ve daha düşük IL-6 düzeylerine sahip oldukları bulundu. GSH, IL-1β, TNF-α, T3 ve T4 düzeyleri bakımından yaş grupları arasında farkın olmadığı saptandı. Sonuç olarak, koyunlarda kan lipid peroksidasyonu ve IL-6 düzeylerine yaşın etkisi olduğu söylenebilir.

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Cite This Article

SALİM, M., DURMUŞ, İ., BAŞEĞMEZ, M., KÜÇÜKKURT, İ., ERYAVUZ, A. (2021). Effects of Age on The Concentrations of Plasma Cytokines and Lipidperoxidation in Sheep. Kocatepe Veteriner Dergisi, Cilt: 14 - Sayı: 1, 37–44. https://ajindex.com/articles/124583

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