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Journals / Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi / 2026 / Cilt: 17 Sayı: 3

Antimicrobial Activity and Chemical Composition of Essential Oil Extracted from Hyoscyamus niger L. Inflorescence

Sefa Gözcü(ERZINCAN UNIVERSITY, FACULTY OF PHARMACY)0000-0002-0735-4229
Zeynep Akşit(ERZINCAN BINALI YILDIRIM UNIVERSITY)0000-0002-0349-0223
Hüseyin Akşit(ERZINCAN BINALI YILDIRIM UNIVERSITY)0000-0002-1509-851X
Pages
751–760
Publication Date
2024-12-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results suggest that H. niger inflorescence essential oil has potential as an antibacterial agent, highlighting the importance of exploring plant-derived compounds as alternatives to traditional antibiotics in combating multidrug-resistant bacteria.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:This study aimed to analyze the chemical composition and evaluate the antibacterial activity of essential oils extracted from the H. niger inflorescence collected from Erzincan, Türkiye.
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Key Findings & Data:The essential oils were extracted using hydrodistillation and analyzed by GC-MS, identifying 23 components, with major constituents being 10-heneicosene (35.72%), phytol (20.50%), and acetic acid, butyl ester (10.10%).
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Conclusion & Impact:The results suggest that H. niger inflorescence essential oil has potential as an antibacterial agent, highlighting the importance of exploring plant-derived compounds as alternatives to traditional antibiotics in combating multidrug-resistant bacteria.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Hyoscyamus niger L. · Essential oil · Antibacterial

Abstract

This study aimed to analyze the chemical composition and evaluate the antibacterial activity of essential oils extracted from the H. niger inflorescence collected from Erzincan, Türkiye. The essential oils were extracted using hydrodistillation and analyzed by GC-MS, identifying 23 components, with major constituents being 10-heneicosene (35.72%), phytol (20.50%), and acetic acid, butyl ester (10.10%). The antibacterial activity was tested against six bacterial strains, including Staphylococcus aureus, Clostridium perfringens, Enterococcus faecalis, Bacillus cereus, Listeria monocytogenes, and Escherichia coli, using the disc diffusion method. The H. niger inflorescence essential oil exhibited moderate antibacterial activity, specifically against Clostridium perfringens, with a zone of inhibition of 11.7 ± 1.2 mm compared to the positive control imipenem (17.0±1.0 mm). The results suggest that H. niger inflorescence essential oil has potential as an antibacterial agent, highlighting the importance of exploring plant-derived compounds as alternatives to traditional antibiotics in combating multidrug-resistant bacteria.

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Cite This Article

Gözcü, S., Akşit, Z., Akşit, H. (2024). Antimicrobial Activity and Chemical Composition of Essential Oil Extracted from Hyoscyamus niger L. Inflorescence. Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Cilt: 17 Sayı: 3, 751–760. https://doi.org/10.18185/erzifbed.1522296

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