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Journals / Turkish Journal of Veterinary and Animal Sciences / 2014 / Cilt: 38 - Sayı: 4

Pathotypic characterization of the Newcastle disease virus isolated from commercial poultry in northwest Iran

Elham AHMADI
Seyed Ali POURBAKHSH
Malahat AHMADI
Alireza TALEBI
Pages
383–387
Publication Date
2014-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

These results confirmed that virulent NDVs are circulating in the region, causing economic losses within the poultry industry.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Despite vaccination, outbreaks of Newcastle disease in commercial poultry flocks in northwest Iran have been regularly reported in recent years.
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Key Findings & Data:Ten Newcastle disease virus isolates were obtained from various districts of northwest Iran in 2010.
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Conclusion & Impact:These results confirmed that virulent NDVs are circulating in the region, causing economic losses within the poultry industry.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Newcastle disease virus · northwest Iran · fusion protein

Abstract

Despite vaccination, outbreaks of Newcastle disease in commercial poultry flocks in northwest Iran have been regularly reported in recent years. This research was proposed in order to characterize, through a molecular approach, the genetic nature of strains of Newcastle disease virus isolated from commercial poultry flocks in northwest Iran. Ten Newcastle disease virus isolates were obtained from various districts of northwest Iran in 2010. The isolates were screened with F gene-targeting reverse transcription polymerase chain reaction (RT-PCR). The amplified products of virulent strains were sequenced. The deduced amino acid sequence of the fusion protein cleavage site indicated the presence of motif 112R-R-Q-R-R.F117, typical for velogenic strains of NDV. These results confirmed that virulent NDVs are circulating in the region, causing economic losses within the poultry industry.

Özet

Despite vaccination, outbreaks of Newcastle disease in commercial poultry flocks in northwest Iran have been regularly reported in recent years. This research was proposed in order to characterize, through a molecular approach, the genetic nature of strains of Newcastle disease virus isolated from commercial poultry flocks in northwest Iran. Ten Newcastle disease virus isolates were obtained from various districts of northwest Iran in 2010. The isolates were screened with F gene-targeting reverse transcription polymerase chain reaction (RT-PCR). The amplified products of virulent strains were sequenced. The deduced amino acid sequence of the fusion protein cleavage site indicated the presence of motif 112R-R-Q-R-R.F117, typical for velogenic strains of NDV. These results confirmed that virulent NDVs are circulating in the region, causing economic losses within the poultry industry.

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Cite This Article

AHMADI, E., POURBAKHSH, S. A., AHMADI, M., TALEBI, A. (2014). Pathotypic characterization of the Newcastle disease virus isolated from commercial poultry in northwest Iran. Turkish Journal of Veterinary and Animal Sciences, Cilt: 38 - Sayı: 4, 383–387. https://ajindex.com/articles/121557

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