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Journals / Journal of Basic and Clinical Health Sciences / 2026 / Volume: 7 Issue: 1

Institutional Accuracy Matters: How the Correlation between Frozen Section and Final Pathology Depends on Institutes while Evaluating Lymph Node Involvement in Endometrial Adenocarcinoma

Alpay Yılmaz(Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Obstetrics and Gynecology)0000-0001-9265-7752
Aysegul Gulbahar(Izmir Katip Celebi University Ataturk Training and Research Hospital, Department of Obstetrics and Gynecology)0000-0001-6533-6195
Pages
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Publication Date
2023-01-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Overall, the frozen section analysis had an accuracy of 70% for tumor grades.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background and Purpose: The frozen section analysis results help determine the appropriate surgery and treatment for patients with endometrial adenocarcinoma.
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Key Findings & Data:Methods: This study included 357 patients with endometrial adenocarcinoma who underwent operation, follow-up, and treatment at our hospital.
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Conclusion & Impact:Overall, the frozen section analysis had an accuracy of 70% for tumor grades.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Endometrial cancer · neoplasm · tumor staging

Abstract

Background and Purpose: The frozen section analysis results help determine the appropriate surgery and treatment for patients with endometrial adenocarcinoma. This study investigates the degree of compliance between the results of frozen section analysis and final pathology reports in patients with endometrial cancer. Methods: This study included 357 patients with endometrial adenocarcinoma who underwent operation, follow-up, and treatment at our hospital. The patients’ demographic, clinical, surgical, and pathological data were retrospectively analyzed. We compared the results of the frozen section and pathological specimens in terms of final pathology, tumor grade, myometrial invasion, tumor size, and lymphovascular system involvement (LVSI). Results: The frozen section analysis and final pathology results for tumor size and LVSI were significantly correlated when patients were divided by tumor type (tumor size: P=0.006, LVSI: P=0.024) or by risk for lymph node involvement (P=0.000). Overall, the frozen section analysis had an accuracy of 70% for tumor grades. The histological results of the frozen section analysis had an accuracy of 77.1% for type 1 tumors and 72.7% for type 2 tumors. Overall, the frozen section analysis had an accuracy of 95% for myometrial invasion. Conclusion: Intraoperative frozen section analysis can prevent unnecessary lymph node dissection when performed at qualified institutions.

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Cite This Article

Yılmaz, A., Gulbahar, A. (2023). Institutional Accuracy Matters: How the Correlation between Frozen Section and Final Pathology Depends on Institutes while Evaluating Lymph Node Involvement in Endometrial Adenocarcinoma. Journal of Basic and Clinical Health Sciences, Volume: 7 Issue: 1. https://doi.org/10.30621/jbachs.1102375

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