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Journals / Journal of Basic and Clinical Health Sciences / 2026 / Volume: 9 Issue: 2

Impact of Hemoglobin–Albumin–Lymphocyte–Platelet (HALP) Score on Mortality in Above-Ankle Amputation of Diabetic Foot Infection

Hilal Yağar(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0001-5544-0458
Abdussamed Vural(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0003-4506-916X
Turgut Dolanbay(NİĞDE ÖMER HALİSDEMİR ÜNİVERSİTESİ, TIP FAKÜLTESİ)0000-0002-4092-1192
Pages
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Publication Date
2025-05-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Female gender and a HALP score of less than 21.55 and older age than 65 estimates a 20.2% overall 1-year mortality risk (Nagelkerke R square: 0.202).

📌 3 Key Takeaways

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Objective & Hypothesis:Background and Purpose: :Diabetic foot ulcers are one of the important reasons for amputations The hemoglobin–albumin–lymphocyte–platelet (HALP) score is a marker of the inflammatory and nutritional status of the individual.
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Key Findings & Data:Methods: The demographic data (age, sex), deaths during hospitalization, laboratory values and mortality through 3-6-9-12 months were recorded.
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Conclusion & Impact:Female gender and a HALP score of less than 21.55 and older age than 65 estimates a 20.2% overall 1-year mortality risk (Nagelkerke R square: 0.202).
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:diabetic foot infection · HALP score · prognosis

Abstract

Background and Purpose: :Diabetic foot ulcers are one of the important reasons for amputations The hemoglobin–albumin–lymphocyte–platelet (HALP) score is a marker of the inflammatory and nutritional status of the individual. Aim of this study is to investigate the relationship between the HALP score and mortality in patients undergoing above-ankle amputation due to diabetic foot infection. Methods: The demographic data (age, sex), deaths during hospitalization, laboratory values and mortality through 3-6-9-12 months were recorded. Chi square and t test were used for categorical comparation and logistic regression tests were used for mortality risk estimation. Results:. The mortality rates in hospital and in the 3rd, 6th, 9th, and 12th months were 13.1%, 37.7%, 48.5%, 53.8%, and 56.2%. HALP score below 21.55 had a 1-year mortality risk that was 2.975 times than that of score above 21.55 (odds ratio=2.975, 95% CI [1.252-7.069]; p=0.014). Female gender and a HALP score of less than 21.55 and older age than 65 estimates a 20.2% overall 1-year mortality risk (Nagelkerke R square: 0.202). Conclusion: The HALP score is an essential predictor of prognosis in patients undergoing amputation for diabetic foot ulcers. Also; older age and female gender are independent risk factors for 1-year mortality.

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Cite This Article

Yağar, H., Vural, A., Dolanbay, T. (2025). Impact of Hemoglobin–Albumin–Lymphocyte–Platelet (HALP) Score on Mortality in Above-Ankle Amputation of Diabetic Foot Infection. Journal of Basic and Clinical Health Sciences, Volume: 9 Issue: 2. https://doi.org/10.30621/jbachs.1451540

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