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Journals / Dicle Tıp Dergisi / 2015 / Cilt: 42 Sayı: 1

Clinical and laboratory characteristics of children with Kawasaki disease

Kawasaki hastalığı bulunan çocukların klinik ve laboratuvar özellikleri

Fatih Akın
Melike Emiroğlu
Ahmet Sert
Şükrü Arslan
Ece Solak
Pages
28–35
Publication Date
2015-05-09
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Key words: Kawasaki disease, vasculitis, BCG reaction, children

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: In this study, we aimed to evaluate clinical and laboratory characteristics of patients with Kawasaki disease (KD) in Konya region of Turkey.
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Key Findings & Data:Methods: The hospital records of patients who were hospitalized with the diagnosis of KD in the Pediatrics Clinics of Konya Training and Research Hospital between May 2010 and June 2012 were reviewed retrospectively.
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Conclusion & Impact:Key words: Kawasaki disease, vasculitis, BCG reaction, children
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Kawasaki hastalığı · vaskülit · BCG reaksiyonu

Abstract

Objective: In this study, we aimed to evaluate clinical and laboratory characteristics of patients with Kawasaki disease (KD) in Konya region of Turkey. Methods: The hospital records of patients who were hospitalized with the diagnosis of KD in the Pediatrics Clinics of Konya Training and Research Hospital between May 2010 and June 2012 were reviewed retrospectively. Results: Seven cases were found to have the diagnosis of KD, two of whom were incomplete KD. Oropharynx changes were the most common (100%) feature in our patients. Five (71%) patients had bulbar conjunctivitis. Three (43%) patients had erythema at the site of BCG inoculation. Adenopathy was present in all of our patients with the classical form. A desquamation was observed in one case at the seventh day of fever. No cardiac manifestation was seen. Elevated erythrocyte sedimentation rate and thrombocytosis were present in all patients. All of the patients were received intravenous immunoglobulin in the first ten days of the fever. Conclusion: KD should be considered as a possible diagnosis in any child presenting with prolonged fever. BCG reaction can be attributed as a diagnostic criterion for incomplete form of the disease especially in countries where BCG vaccination is routinely performed. Early treatment is essential to prevent cardiovascular complications. Key words: Kawasaki disease, vasculitis, BCG reaction, children

Özet

Amaç: Bu çalışmada, kliniğimizde Kawasaki hastalığı (KH) tanısıyla takip ettiğimiz vakalarımızın klinik ve laboratuvar özelliklerini sunmayı amaçladık. Yöntemler: Konya Eğitim ve Araştırma Hastanesi Çocuk Sağlığı ve Hastalıkları Kliniği’ne Mayıs 2010 ve Haziran 2012 tarihleri arasında KH tanısıyla yatırılarak takip edilen hastaların kayıtları retrospektif olarak incelendi.Bulgular: Yedi vakanın Kawasaki hastalığı tanısıyla izlendiği tespit edildi. Bu vakaların ikisi inkomplet Kawasaki hastalığı tanısı almıştı. Hastalarımızın tümünde (%100) orafarenks bulguları mevcuttu. Beş hastada (%71) bulbar konjonktivit vardı. Üç hastada (%43) BCG aşı yerinde eritem gözlendi. Klasik Kawasaki hastalığı tanısı alanların tümünde servikal adenopati mevcuttu. Bir hastada ateşin yedinci gününde ortaya çıkan ve bir hafta içinde düzelen periungual deskuamasyon gözlendi. Tüm hastalarımızda yüksek eritrosit sedimentasyon hızı ve trombositoz mevcuttu. Takipleri süresince hastaların hiçbirinde kardiak komplikasyon gözlenmedi. Hastalarımızın tümü ateşin ilk 10 günü içinde IVIG tedavisi almıştı.Sonuç: Uzamış ateş şikayetiyle gelen her hastada ayırıcı tanıda KH düşünülmelidir. BCG aşısının rutin olarak uygulandığı ülkelerde BCG aşı yerinde gelişen eritem özellikle inkomplet KH’nda tanı kriteri olarak kullanılabilir. Kardiyovaskuler komplikasyonların gelişmesini önlemek açısından hastalığın erken tanısı tedavisinin başlanması çok önemlidir

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Cite This Article

Akın, F., Emiroğlu, M., Sert, A., Arslan, Ş., Solak, E. (2015). Clinical and laboratory characteristics of children with Kawasaki disease. Dicle Tıp Dergisi, Cilt: 42 Sayı: 1, 28–35. https://doi.org/10.5798/diclemedj.0921.2015.01.0525

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