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Journals / Dicle Tıp Dergisi / 2026 / Cilt: 46 Sayı: 1

Ciprofloxacin is not a better choice in the patients with diabetes suffering urinary tract infection

Kader Ugur
İsa Ahmet Bal0000-0002-0893-8218
Ayse Sagmak Tartar0000-0002-9052-7986
Nevzat Gozel0000-0001-7326-6860
Bedrettin Orhan0000-0003-3970-2344
Emir Donder0000-0003-2537-6023
Abdullah Mubin Ozercan0000-0002-6968-7838
Pages
65–72
Publication Date
2019-03-03
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In diabetic patients, it will be more appropriate to give antibiotherapy in urinary system infections based on the antibacterial susceptibility test results.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study is to determine antibacterial susceptibilities of Gram-negative bacteria isolated from diabetic and non-diabetic patients as infectious agents of community-acquired urinary tract infections (UTI) and to compare their rates of resistance to the antibiotics frequently used in empirical treatment.
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Key Findings & Data:Methods: Ninety-six diabetic and sixty-eight non-diabetic (total n=164) patients’ data were evaluated retrospectively who diagnosed as community-acquired urinary system infection and consulted to outpatient clinics of Department of Endocrinology and Infectious Diseases of Firat University School of Medicine between January 1st , 2014 and December 31st, 2014 whose urine cultures demonstrated Gram-negative bacteria were included in the study.
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Conclusion & Impact:In diabetic patients, it will be more appropriate to give antibiotherapy in urinary system infections based on the antibacterial susceptibility test results.
🔬Design:Araştırma Makalesi
📍Scope:2014 Verileri
⚙️Variables:Diabetes mellitus · urinary tract infection

Özet

Objective: The aim of this study is to determine antibacterial susceptibilities of Gram-negative bacteria isolated from diabetic and non-diabetic patients as infectious agents of community-acquired urinary tract infections (UTI) and to compare their rates of resistance to the antibiotics frequently used in empirical treatment. Methods: Ninety-six diabetic and sixty-eight non-diabetic (total n=164) patients’ data were evaluated retrospectively who diagnosed as community-acquired urinary system infection and consulted to outpatient clinics of Department of Endocrinology and Infectious Diseases of Firat University School of Medicine between January 1st , 2014 and December 31st, 2014 whose urine cultures demonstrated Gram-negative bacteria were included in the study. Antibiotic susceptibilities of the isolated bacteria were determined using Vitek 2 automated system and the results were evaluated as sensitive and resistant. Results: In both diabetic and non-diabetic patient groups, most frequently Escherichia coli (88.5% in diabetic and 85.3% in non-diabetic groups) were isolated. In the diabetic group, microorganisms mostly demonstrated the highest rates of resistance against ampicillin, cephalosporins, ciprofloxacin, amoxicillin-clavulanic acid and in the non-diabetic group ampicillin, amoxicillin-clavulanic acid, cefuroxime and trimethoprim-sulfamethoxazole. Conclusion: Resistance to ciprofloxacin was at a significantly higher rate in the diabetic group. In diabetic patients, it will be more appropriate to give antibiotherapy in urinary system infections based on the antibacterial susceptibility test results.

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Cite This Article

Ugur, K., Bal, İ. A., Tartar, A. S., Gozel, N., Orhan, B., Donder, E., Ozercan, A. M. (2019). Ciprofloxacin is not a better choice in the patients with diabetes suffering urinary tract infection. Dicle Tıp Dergisi, Cilt: 46 Sayı: 1, 65–72. https://doi.org/10.5798/dicletip.474694

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