Key Findings & Data:NOS, konak savunmasında ve vasküler yapının sürdürülmesinde önemli rol oynamaktadır.
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Conclusion & Impact:Çalışmamızın amacı bruselloz hastalarında ve kontrol grubunda ADMA düzeyinin araştırılmasıdır.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Asimetrik Dimetilarjinin · bruselloz
Özet
Amaç: Asimetrik dimetilarginin (ADMA), nitrik oksit sentazın (NOS) ana endojen inhibitörüdür. NOS, konak savunmasında ve vasküler yapının sürdürülmesinde önemli rol oynamaktadır. Yüksek ADMA düzeylerinin endoteldis fonksiyonu ile ilişkili olduğu ve çeşitli hastalıklarda rol aldığı gösterilmiştir. Brucellaspp.’nin neden olduğu zoonoz bir hastalık olan bruselloz, vaskülopati olarak kendini gösterebilmektedir. Ancak, bruselloz ile ADMA arasındaki ilişki ile ilgili yeterli veri bulunmamaktadır. Çalışmamızın amacı bruselloz hastalarında ve kontrol grubunda ADMA düzeyinin araştırılmasıdır.
Sezgin, M., Aydın, M., Karakeçili, F., Çıkman, A., Gülhan, B., Arslan, Y. K. (2019). Bruselloz Hastalarında Asimetrik Dimetilarjinin (ADMA) Düzeylerinin Araştırılması. Dicle Tıp Dergisi, Cilt: 46 Sayı: 3, 479–487. https://doi.org/10.5798/dicletip.620502
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