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Journals / Dicle Tıp Dergisi / 2020 / Cilt: 47 Sayı: 1

The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio

Nizamettin Selçuk Yelgeç(İSTANBUL DR. SİYAMİ ERSEK GÖĞÜS KALP VE DAMAR CERRAHİSİ SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ)
Mehmet Baran Karataş(dr sıyami erse)
Can Yücel Karabay(dr. siyami ersek)
Yiğit Çanga(dr. siyami ersek)
Ali Nazmi Çalık(dr. siyami ersek)
Barış Şimşek(dr. siyami ersek)
Özge Güzelburç(dr. siyami ersek)
Ayşe Emre(dr. siyami ersek)
Pages
1–9
Publication Date
2020-03-17
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

High values of NLR may indicate a poor prognosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to open-heart surgery for patients with severe symptomatic aortic stenosis who has a high risk for surgery.
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Key Findings & Data:Methods: 148 patients who have been performed TAVR at our institution between 2010 and 2018, analyzed retrospectively.
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Conclusion & Impact:High values of NLR may indicate a poor prognosis.
🔬Design:Araştırma Makalesi
📍Scope:2010 Verileri
⚙️Variables:Neutrophil to lymphocyte ratio · Transcatheter aortic valve implantation

Özet

Objective: Transcatheter aortic valve replacement (TAVR) is a less invasive alternative to open-heart surgery for patients with severe symptomatic aortic stenosis who has a high risk for surgery. Acute kidney injury (AKI) is not a rare complication after TAVR and has been associated with poorer outcomes and survival. This study aims to analyze the relation between serum Neutrophil-lymphocyte ratio (NLR) and AKI in Post-TAVR patients. Methods: 148 patients who have been performed TAVR at our institution between 2010 and 2018, analyzed retrospectively. We divided the patients into two groups. Group 1 (n=116): The patients who did not develop AKI after TAVR procedure (control group) and Group 2 (n=32): The patients who developed AKI after TAVR. The independent relation between possible independent predictors of AKI in post-TAVI patients was analyzed by regression analysis. Results: 32 patients (22%) suffered from AKI after TAVR during hospitalization. NLR was significantly associated with the development of AKI (3.22 ±0.62 vs. 2.42 ± 0.45, p<0.01). In multivariate regression analysis, NLR (OR: 1.79, p=0,01), diabetes mellitus (OR: 1.41, p=0,01), and preprocedural creatinine levels (OR: 1.86, p=0,01) were found to be independently correlated with the development of AKI after TAVR. Conclusion: This study suggests that High NLR was independently associated with AKI in post-TAVR patients. High values of NLR may indicate a poor prognosis.

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Cite This Article

Yelgeç, N. S., Karataş, M. B., Karabay, C. Y., Çanga, Y., Çalık, A. N., Şimşek, B., Güzelburç, Ö., Emre, A. (2020). The Relationship Between Acute Renal Failure After Transcatheter Aortic Valve Replacement And Preprocedural Neutrophil To Lymphocyte Ratio. Dicle Tıp Dergisi, Cilt: 47 Sayı: 1, 1–9. https://doi.org/10.5798/dicletip.705532

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