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Journals / Akademik Gastroenteroloji Dergisi / 2026 / Cilt: 5 Sayı: 1

Plasma cytokine levels in ulcerative colitis

Ülseratif kolitli hastalarda plazma sitokin düzeyleri

Vedat Göral
Tahir Çelenk
Abdurahman Kaplan
Dede Şit
Pages
16–19
Publication Date
2006-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different in the patients and control groups (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background/aim: Some immunological factors are responsible in the pathogenesis of ulcerative colitis.
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Key Findings & Data:Materials and method: In this study, the levels of IL-1 beta, IL-2Rsp, IL-6, IL-8, IL-10, TNF-alpha were studied 20 patients with ulcerative colitis (mean age 36.2 years, 9 women, 11 men) and 20 healthy individuals (mean age 27.2 years, 11 women, 9 men).
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Conclusion & Impact:Results: We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different in the patients and control groups (p
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Ülseratif kolit · sitokinler · Ulcerative colitis

Abstract

Background/aim: Some immunological factors are responsible in the pathogenesis of ulcerative colitis. There are some relationship between cytokines and ulcerative colitis. Materials and method: In this study, the levels of IL-1 beta, IL-2Rsp, IL-6, IL-8, IL-10, TNF-alpha were studied 20 patients with ulcerative colitis (mean age 36.2 years, 9 women, 11 men) and 20 healthy individuals (mean age 27.2 years, 11 women, 9 men). Results: We established that IL-2Rsp, IL-6, IL-8 and IL-10 levels were different in the patients and control groups (p

Özet

Giriş ve amaç: Ülseratif kolitin etyopatogenezinden sorumlu faktörlerden birisi de immünolojik faktörlerdir. Sitokinler ile bu hastalık arasında ilişki vardır. Gereç ve yöntem: Bu çalışmada 20 ülseratif kolit vakası (ort. yaş 36.2, 9 kadın, 11 erkek) ve 20 kişilik (ort. yaş 27.2, 11 kadın, 9 erkek) sağlıklı kontrol grubunda; IL-1 beta, IL-2Rsp, IL-6, IL-8, IL-10, TNF-alfa düzeyleri çalışıldı. Bulgular: IL-2Rsp, IL-6, IL-8 ve IL-10 düzeyleri hasta ve kontrol grubunda farklı bulundu (p < 0.005). TNF-alfa ve IL-1 beta seviyeleri her 2 grupta da aynı bulundu. Sonuç: Bu sonuçlara göre, IL-2Rsp, IL-6, IL-8 ve IL-10 ülseratif kolitde rol oynayan önemli sitokinlerdir. Bu sitokinlerin hastalığın, tanı, takip ve prognozunda önemli rol oynacağını düşünmekteyiz.

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Cite This Article

Göral, V., Çelenk, T., Kaplan, A., Şit, D. (2006). Plasma cytokine levels in ulcerative colitis. Akademik Gastroenteroloji Dergisi, Cilt: 5 Sayı: 1, 16–19. https://ajindex.com/articles/1187737

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