Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2025 / Cilt: 51 Sayı: 2

Performance of Generative AI Models on Cardiology Practice in Emergency Service: A Pilot Evaluation of GPT-4.o and Gemini-1.5-Flash

Kardiyak Acil Durumların Yönetiminde ChatGPT ve Gemini

Şeyda Günay Polatkan(Bursa UludaBursa Uludag University, Faculty of Medicine, Departmant of Cardiology, Bursa, Türkiye.g Universitesi)0000-0003-0012-345X
Deniz Sığırlı(Bursa Uludag University, Faculty of Medicine, Departmant of Biostatistics, Bursa, Türkiye.)0000-0002-4006-3263
Vahide Aslıhan Durak(Bursa Uludag University, Faculty of Medicine, Departmant of Emergency Medicine, Bursa, Türkiye.)0000-0003-0836-7862
Çetin Alak(Bursa Uludag University, Faculty of Medicine, Departmant of Cardiology, Bursa, Türkiye.)0000-0003-1875-2078
Irem Iris Kan(Bursa Uludag University, Faculty of Medicine, Departmant of Cardiovascular surgery, Bursa, Türkiye.)0000-0002-1600-9531
Pages
239–246
Publication Date
2025-08-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although on the whole GPT-4.o outperformed Gemini-1.5-Flash, both models demonstrated an ability to comprehend the case scenarios and provided reasonable answers.

📌 3 Key Takeaways

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Objective & Hypothesis:In healthcare, emergent clinical decision-making is complex and large language models (LLMs) may enhance both the quality and efficiency of care by aiding physicians.
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Key Findings & Data:This study aims to compare the diagnostic and treatment capabilities of GPT-4.o and Gemini-1.5-Flash and to evaluate the readability of the responses for cardiac emergencies.
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Conclusion & Impact:Although on the whole GPT-4.o outperformed Gemini-1.5-Flash, both models demonstrated an ability to comprehend the case scenarios and provided reasonable answers.
🔬Design:Modeling & Simulation
📍Scope:Comprehensive Sample
⚙️Variables:kardiyoloji · karar verme · yapay zeka

Abstract

In healthcare, emergent clinical decision-making is complex and large language models (LLMs) may enhance both the quality and efficiency of care by aiding physicians. Case scenario-based multiple choice questions (CS-MCQs) are valuable for testing analytical skills and knowledge integration. Moreover, readability is as important as content accuracy. This study aims to compare the diagnostic and treatment capabilities of GPT-4.o and Gemini-1.5-Flash and to evaluate the readability of the responses for cardiac emergencies. A total of 70 single-answer MCQs were randomly selected from the Medscape Case Challenges and ECG Challenges series. The questions were about cardiac emergencies and were further categorized into four subgroups according to whether the question included a case presentation or an image, or not. ChatGPT and Gemini platforms were used to assess the selected questions. The Flesch–Kincaid Grade Level (FKGL) and Flesch Reading Ease (FRE) scores were utilized to evaluate the readability of the responses. GPT-4.o had a correct response rate of 65.7%, outperforming Gemini-1.5-Flash, which had a 58.6% correct response rate (p=0.010). When comparing by question type, GPT-4.o was inferior to Gemini-1.5-Flash only for non-case questions (52.5% vs. 62.5%, p=0.011). For all other question types, there were no significant performance differences between the two models (p>0.05). Both models performed better on easy questions compared to difficult ones, and on questions without images compared to those with images. Additionally, while GPT-4.o performed better on case questions than non-case questions. Gemini-1.5-Flash’s FRE score was higher than GPT-4.o’s (median [min-max], 23.75 [0-64.60] vs. 17.0 [0-56.60], p<0.001). Although on the whole GPT-4.o outperformed Gemini-1.5-Flash, both models demonstrated an ability to comprehend the case scenarios and provided reasonable answers.

Özet

Sağlık hizmetlerinde, acil klinik karar alma karmaşıktır ve büyük dil modelleri (LLM'ler) hekimlere yardımcı olarak hem bakımın kalitesini hem de verimliliğini artırabilir. Vaka senaryosuna dayalı çoktan seçmeli sorular (VS-ÇSS), analitik becerileri ve bilgi bütünleştirmeyi test etmek için değerlidir. Ayrıca, okunabilirlik, içerik doğruluğu kadar önemlidir. Bu çalışma, GPT-4.o ve Gemini-1.5-Flash'ın tanı ve tedavi yeteneklerini karşılaştırmayı ve kardiyak acil durumlar için yanıtların okunabilirliğini değerlendirmeyi amaçlamaktadır. Medscape Vaka Zorlukları ve EKG Zorlukları serilerinden toplam 70 tek cevaplı ÇSS rastgele seçildi. Sorular kardiyak acil durumlarla ilgiliydi ve sorunun bir vaka sunumu veya bir görüntü içerip içermemesine göre dört alt gruba ayrıldı. Seçilen soruları değerlendirmek için CahtGPT ve Gemini platformları kullanıldı. Yanıtların okunabilirliğini değerlendirmek için Flesch-Kincaid Sınıf Düzeyi (FKGL) ve Flesch Okuma Kolaylığı (FRE) puanları kullanıldı. GPT-4.o'nun doğru yanıt oranı %65,7'ydi ve %58,6 doğru yanıt oranına sahip Gemini-1.5-Flash'ı geride bıraktı (p=0,010). Soru türüne göre karşılaştırıldığında, GPT-4.o yalnızca vaka dışı sorularda Gemini-1.5-Flash'tan daha düşüktü (%52,5'e karşı %62,5, p=0,011). Diğer tüm soru türleri için, iki model arasında önemli bir performans farkı yoktu (p>0,05). Her iki model de kolay sorularda zor sorulara göre ve resimsiz sorularda resimli sorulara göre daha iyi performans gösterdi. Ek olarak, GPT-4.o vaka dışı sorulara göre vaka sorularında daha iyi performans gösterdi. Gemini-1.5-Flash'ın FRE puanı GPT-4.o'dan daha yüksekti (ortanca [min-maks], 23.75 [0-64.60] - 17.0 [0-56.60], p<0.001). Her ne kadar toplamda GPT-4.o, Gemini-1.5-Flash'tan daha iyi performans gösterse de, her iki model de durum senaryolarını anlama becerisi gösterdi ve makul yanıtlar sağladı.

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Cite This Article

Polatkan, Ş. G., Sığırlı, D., Durak, V. A., Alak, Ç., Kan, I. I., *, Ş. G. P. (2025). Performance of Generative AI Models on Cardiology Practice in Emergency Service: A Pilot Evaluation of GPT-4.o and Gemini-1.5-Flash. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 51 Sayı: 2, 239–246. https://doi.org/10.32708/uutfd.1718121

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