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Journals / Uludağ Üniversitesi Tıp Fakültesi Dergisi / 2026 / Cilt: 52

Behçet's Disease in Idiopathic Intracranial Hypertension Without Cerebral Venous Sinus Thrombosis: Retrospective Results of a Tertiary Headache Center

İdiopatik Intracranial Hipertansiyonda Serebral Venöz Sinüz Trombozu Olmaksızın Behçet Hasatalığı: Üçüncü Basamak Bir Baş Ağrısı Merkezinin Retrospektif Sonuçları

Fatma Yılmaz Can(Etlik City Hospital, Department of Neurology, Ankara, Türkiye.)0000-0003-0995-4911
Mehmet Fevzi Öztekin(Etlik City Hospital, Department of Neurology, Ankara, Türkiye.)0000-0003-3582-2832
Hacı Asım Kılıç(Etlik City Hospital, Department of Neurology, Ankara, Türkiye.)0000-0002-5301-7039
Aynur Turan(Etlik City Hospital, Department of Radiology, Ankara, Türkiye.)0000-0001-6654-3129
Pages
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Publication Date
2026-07-23
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We recommend questioning IIH patients for BD symptoms in regions where BD is endemic.

📌 3 Key Takeaways

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Objective & Hypothesis:In our clinic, we frequently observed the comorbidity of Behçet's disease (BD) without cerebral vein thrombosis in patients with idiopathic intracranial hypertension (IIH).
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Key Findings & Data:The medical records of 98 patients diagnosed with IIH were retrospectively reviewed.
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Conclusion & Impact:We recommend questioning IIH patients for BD symptoms in regions where BD is endemic.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Behçet Hastalığı · idiopatik intrakranial hipertansiyon · inflamasyon

Abstract

In our clinic, we frequently observed the comorbidity of Behçet's disease (BD) without cerebral vein thrombosis in patients with idiopathic intracranial hypertension (IIH). This study aimed to investigate the comorbidity of isolated BD in patients with IIH. The medical records of 98 patients diagnosed with IIH were retrospectively reviewed. IIH was diagnosed by an experienced neurologist. At the diagnosis stage, patients who responded to the question "Do you have any comorbidities?" with a statement of BD had their diagnoses confirmed by a rheumatologist. The radiological images of patients diagnosed with BD were reconfirmed by a neuroradiologist, and neuro-Behçet's (NBD) disease was excluded. Isolated BD was diagnosed in 4 of 98 IIH patients (4.1%). Ninety-two of the IIH patients were female (93.9%). The mean age of the patients was 36.7±12 (18-65) years, and their mean body mass index (BMI) was 32.39 (21-49). Four BD patients were female. There was no significant difference between those with BD and those without BD regarding gender (p= 1.0). The average age of those with BD was 43.50, and the average age of those without BD was 36.41, and there was no significant difference between them (p=0.167). The mean BMI of IIH patients with BD was 35.40, while the mean BMI of IIH patients without BD was 32.26. No significant difference was found between them (p=0.323). We found a 4.1% prevalence of BD in patients with IIH. We recommend questioning IIH patients for BD symptoms in regions where BD is endemic.

Özet

Kliniğimizde idiyopatik intrakranial hipertansiyonlu (İİH) hastalarda sıklıkla serebral ven trombozu olmaksızın Behçet hastalığının (BH) eşlik ettiğini gözlemledik. Bu çalışmada, İİH'li hastalarda izole BH prevalansını araştırmayı amaçladık. İİH’li hastalara tanı aşamasında "Eşlik eden bir hastalığınız var mı?" sorusu soruldu. BH olduğunu beyan eden hastaların tanıları romatolog tarafından konfirme edildi, hastalık tanısı doğulandı. BH komorbiditesi olanlarin radyolojik görüntüleri tekrar tecrubeli bir nöroradyolog tarafından gözden geçirilerek nöro-Behçet hastalığı (NBH) ekaret edildi. Doksansekiz İİH hastasının 4'üne (%4,1) izole BH tanısı konuldu. Hastalardan 92'si kadın (%93,9), 6'sı erkekti (%6,1). Hastaların yaş ortalaması 36,7±12 (18-65) yıl, vücut kitle indeksi (VKİ) ortalamaları 32,39 (21-49) kg/m2’di. Dört BH’li hasta da kadındı. BH'li hastalar ile BH'siz hastalar arasında cinsiyet açısından anlamlı bir fark yoktu (p=1,0). BH'li hastaların yaş ortalaması 43,50, BH'siz hastaların yaş ortalaması 36,41 yıldı ve aralarında anlamlı bir fark yoktu (p=0,167). BH'li İİH hastalarının ortalama VKİ'si 35,4 kg/m2 iken, BH'siz IIH hastalarının ortalama VKİ'si 32,26 kg/m2’ydi. Aralarında anlamlı bir fark bulunmadı (p=0,323). İİH hastalarında %4,1 oranında BH prevalansı saptadık. BH endemik olduğu bölgelerde İİH hastalarında BH semptomlarının sorgulanmasını öneriyoruz.

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Cite This Article

Can, F. Y., Öztekin, M. F., Kılıç, H. A., Turan, A., *, F. Y. C. (2026). Behçet's Disease in Idiopathic Intracranial Hypertension Without Cerebral Venous Sinus Thrombosis: Retrospective Results of a Tertiary Headache Center. Uludağ Üniversitesi Tıp Fakültesi Dergisi, Cilt: 52. https://doi.org/10.32708/uutfd.1836259

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