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Journals / Balıkesir Medical Journal / 2026 / Cilt: 2 Sayı: 1

Rarely seen autoimmune polyglandular syndrome; Type 3B complicated with celiac disease

Çölyak hastalığı ile komplike nadir görülen otoimmün poliglandüler sendrom; tip3B

Hakan Aydın(Adiyaman University, Training and Research Hospital, Adiyaman, Türkiye)
Zülfükar Bilge(Adiyaman University, Training and Research Hospital, Adiyaman, Türkiye)
Abdullah Algın(Adiyaman University, Training and Research Hospital, Adiyaman, Türkiye)0000-0002-9016-9701
Hüseyin Avni Fındıklı(Adiyaman University, Training and Research Hospital, Adiyaman, Türkiye)
Bünyamin Aydın(Adiyaman University, Training and Research Hospital, Adiyaman, Türkiye)
Pages
1–8
Publication Date
2018-02-11
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we present a rarely seen case of a 32-year-old woman with T1 DM and ATD complicated with CD, which is defined APS type 3B.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases.
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Key Findings & Data:APS type 3 is defined by the presence of autoimmune thyroid disease (ATD) without Addison’s disease and at least one autoimmune disease such as type 1 diabetes mellitus (type 3A), chronic atrophic gastritis, pernicious anemia,autoimmune hepatitis or celiac disease (type 3B), vitiligo, alopecia, myasthenia gravis (type 3C), autoimmune rheumatic disorders, vasculitis (type 3D).
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Conclusion & Impact:Here we present a rarely seen case of a 32-year-old woman with T1 DM and ATD complicated with CD, which is defined APS type 3B.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Otoimmün poliglandüler sendrom · Çölyak hastalığı · Tip 1 diabetes mellitus

Abstract

Autoimmune polyglandular syndrome (APS) is a combination of different autoimmune diseases. APS type 3 is defined by the presence of autoimmune thyroid disease (ATD) without Addison’s disease and at least one autoimmune disease such as type 1 diabetes mellitus (type 3A), chronic atrophic gastritis, pernicious anemia,autoimmune hepatitis or celiac disease (type 3B), vitiligo, alopecia, myasthenia gravis (type 3C), autoimmune rheumatic disorders, vasculitis (type 3D). Celiac disease (CD) is an immune-mediated disease with a strong genetic influence. Type 1 diabetes mellitus (T1DM) and ATD are well established and people suffering from these two diseases are considered at high risk of developing CD. Here we present a rarely seen case of a 32-year-old woman with T1 DM and ATD complicated with CD, which is defined APS type 3B.

Özet

Otoimmün poliglandüler sendrom (OPS) farklı otoimmün hastalıkların kombinasyonudur. Klinik kriterler baz alınarak OPS'nin dört ana tipi tariflenmiştir.Tip 3 formu; Addison hastalığı olmadan, otoimmün tiroid hastalıklarından birine Tip 1 diabetes mellitus (Tip 3A) veya kronik atrofik gastrit, pernisiyöz anemi, çölyak hastalığı, otoimmün hepatit (Tip 3B), vitiligo,alopesi,myastenia graves (Tip 3C), kollajen hastalıklar, vaskülit (Tip 3D) gibi otoimmün hastalıkların eşlik ettiği sendromdur. Çölyak hastalığı (CD), güçlü bir genetik etkiye sahip immün aracılı bir hastalıktır. Tip 1 diabetes mellitus (T1DM) ve OTH, insanların bu hastalıklardan etkilendiği ve Çölyak hastalığı gelişimi için yüksek risk taşıyan iyi tanımlanmış iki hastalıktır. Burada T1DM ve OTH tanıları ile beraber Çölyak hastalığı ile komplike olmuş 32 yaşında kadın bir hastayı yani OPS Tip 3B sendromunu sunmaktayız.

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Cite This Article

Aydın, H., Bilge, Z., Algın, A., Fındıklı, H. A., Aydın, B. (2018). Rarely seen autoimmune polyglandular syndrome; Type 3B complicated with celiac disease. Balıkesir Medical Journal, Cilt: 2 Sayı: 1, 1–8. https://ajindex.com/articles/1150898

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