Journals / Turkish Journal of Medical Sciences / 2019 / Cilt: 49 - Sayı: 6

An old friend: uric acid and its association with fractional flow reserve

Pages
1614–1619
Publication Date
2019-12-01
DOI
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Uric acid levels were assessed in both groups with the enzymatic colorimetric method by clinical chemistry autoanalyzer.Results: The mean UA level was significantly higher in patients whose FFR indicated hemodynamically significant coronary lesions (UA: 5.43 ± 1.29 mg/dL in Group 1 vs. 4.51 ± 1.34 mg/dL in Group 2, P

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Objective & Hypothesis:Background/aim: The aim of this study was to investigate the importance of preprocedural uric acid (UA) level in predicting fractional flow reserve (FFR) results of intermediate coronary lesions in patients with stable coronary artery disease undergoing coronary angiography.Materials and methods: We retrospectively analyzed 293 patients who underwent FFR measurement to determine the significance of intermediate coronary stenosis detected by conventional coronary angiography.
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Key Findings & Data:Patients were divided into 2 groups: Group 1 (n = 127) included patients with FFR of 0.80 (hemodynamically nonsignificant lesions).
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Conclusion & Impact:Uric acid levels were assessed in both groups with the enzymatic colorimetric method by clinical chemistry autoanalyzer.Results: The mean UA level was significantly higher in patients whose FFR indicated hemodynamically significant coronary lesions (UA: 5.43 ± 1.29 mg/dL in Group 1 vs. 4.51 ± 1.34 mg/dL in Group 2, P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Uric acid · fractional flow reserve · intermediate coronary stenosis

Abstract

Background/aim: The aim of this study was to investigate the importance of preprocedural uric acid (UA) level in predicting fractional flow reserve (FFR) results of intermediate coronary lesions in patients with stable coronary artery disease undergoing coronary angiography.Materials and methods: We retrospectively analyzed 293 patients who underwent FFR measurement to determine the significance of intermediate coronary stenosis detected by conventional coronary angiography. Patients were divided into 2 groups: Group 1 (n = 127) included patients with FFR of 0.80 (hemodynamically nonsignificant lesions). Uric acid levels were assessed in both groups with the enzymatic colorimetric method by clinical chemistry autoanalyzer.Results: The mean UA level was significantly higher in patients whose FFR indicated hemodynamically significant coronary lesions (UA: 5.43 ± 1.29 mg/dL in Group 1 vs. 4.51 ± 1.34 mg/dL in Group 2, P

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Cite This Article

TOPAL, S., SEZENÖZ, B., CANDEMİR, M., AÇIKGÖZ, E., AÇIKGÖZ, S. K., BOYACI, N. B. (2019). An old friend: uric acid and its association with fractional flow reserve. Turkish Journal of Medical Sciences, Cilt: 49 - Sayı: 6, 1614–1619. https://ajindex.com/articles/113273

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