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Journals / Ortadoğu Tıp Dergisi / 2026 / Cilt: 10 Sayı: 3

Evaluation of neutrophil / lymphocyte ratio and platelet indexes in endometrium cancer

Endometrium kanserinde nötrofil/lenfosit oranının ve platelet endekslerinin değerlendirilmesi

İlkin Yeral(Kırıkkale Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum AD)0000-0001-8987-1336
Cemile Dayangan Sayan(Kırıkkale Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum AD)
Pages
307–311
Publication Date
2018-09-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a result; inflammation may increase platelet activity and provide a basis for endometrial cancer.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Endometrium cancer is the most common ly seen gynecologic cancer.
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Key Findings & Data:Material and Method: The study included a total of 105 patients.
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Conclusion & Impact:Conclusion: As a result; inflammation may increase platelet activity and provide a basis for endometrial cancer.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:Endometrium kanseri · nötrofil/lenfosit oranı · ortalama platelet volümü

Abstract

Aim: Endometrium cancer is the most common ly seen gynecologic cancer. As in all the cancer processes , chronic inflammation plays an etiological role. Material and Method: The study included a total of 105 patients. T hree groups each consisting 35 patients are formed . Based on the results of endometrial sampling, the patients are groped as benign, hyperplasia and malignant . D ifference s of hematologic parameters between the groups w ere investigated. Results: There was no statistically significant difference between the groups in terms of neutrophil, lymphocyte, and platelet count, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio (p>0. 05). Hemoglobin, mean platelet volume and platelet distribution width values ​​ were found statistically significantly higher in the malignant group (p<0.05). Conclusion: As a result; inflammation may increase platelet activity and provide a basis for endometrial cancer.

Özet

Amaç: Jinekolojik kanserler arasında en sık görüleni endometrium kanseridir. Tüm kanserlerde olduğu gibi, endometrium kanserinde de kronik inflamasyon etyolojik faktör olarak rol oynamaktadır. Gereç ve Yöntem: Çalışmamıza her grupta 35 olmak üzere üç grup ve toplam 105 hasta dahil edildi. Endometrial örnekleme sonuçlarına göre gruplar; benign grup, hiperplazi grubu ve malign grup olarak isimlendirildi. Gruplar arasında hematolojik parametrelerde anlamlı fark olup olmadığı araştırıldı. Bulgular: Nötrofil sayısı, lenfosit sayısı, platelet sayısı, nötrofil/lenfosit oranı ve platelet/lenfosit oranı bakımından gruplar arasında istatistiksel olarak anlamlı bir fark saptanmadı (p>0,05). Hemoglobin, ortalama platelet volümü ve Platelet dağılım genişliği değerleri malign grupta istatistiksel olarak anlamlı derecede yüksek saptandı (p<0,05). Sonuç: Çalışmamızda elde ettiğimiz sonuçlar bize; inflamasyonun, platelet aktivitesini arttırarak endometrium kanserine zemin hazırlayabileceğini düşündürdü.

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Cite This Article

Yeral, İ., Sayan, C. D. (2018). Evaluation of neutrophil / lymphocyte ratio and platelet indexes in endometrium cancer. Ortadoğu Tıp Dergisi, Cilt: 10 Sayı: 3, 307–311. https://doi.org/10.21601/ortadogutipdergisi.445159

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