Journals / Natural and Engineering Sciences / 2023 / Cilt: 8 Sayı: 3

Glucose-Sensitive Biosensor Design by Zinc Ferrite (ZnFe2O4) Nanoparticle-Modified Poly (o-toluidine) Film

Pages
202–213
Publication Date
2023-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It was revealed that ZnFe2O4NP increased the current responses and stability of the Pt/POT electrode.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Glucose oxidase (GOD) immobilized poly(o-toluidine) (POT) coated Pt electrode was designed for glucose-sensitive biosensor.
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Key Findings & Data:Optimal monomer concentration for POT film synthesis was determined as 40 mM and the scanning rate was determined as 50 mV/s.
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Conclusion & Impact:It was revealed that ZnFe2O4NP increased the current responses and stability of the Pt/POT electrode.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Poly(o-toluidine) · glucose oxidase · amperometric biosensor

Abstract

Glucose oxidase (GOD) immobilized poly(o-toluidine) (POT) coated Pt electrode was designed for glucose-sensitive biosensor. Since POT film structure affects enzyme activity, parameters of enzyme immobilization and POT synthesis conditions were optimized. Optimal monomer concentration for POT film synthesis was determined as 40 mM and the scanning rate was determined as 50 mV/s. As for the immobilization process results, GOD, glutaraldehyde (GAL) and chitosan (Chi) concentrations were decided as 2 mg/ml 0.10%, and 0.5% for the Pt/POT electrode. Zinc ferrite nanoparticle (ZnFe2O4NP) was immobilized together with POT film in the presence of GOD enzyme. It was revealed that ZnFe2O4NP increased the current responses and stability of the Pt/POT electrode.

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Cite This Article

OZYİLMAZ, A. T., BAYRAM, E. I. (2023). Glucose-Sensitive Biosensor Design by Zinc Ferrite (ZnFe2O4) Nanoparticle-Modified Poly (o-toluidine) Film. Natural and Engineering Sciences, Cilt: 8 Sayı: 3, 202–213. https://ajindex.com/articles/1021997

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