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Journals / Medicine Science / 2015 / Cilt: 4 Sayı: 3

Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operatıve Serum Calcium and Alkaline Phosphatase Levels

Gulsah Elbuken1, Recep Aktimur2, Kadir Yildirim2, Sude Hatun Aktimur3, Mehmet

Gulsah ELBUKEN
Recep AKTİMUR
Kadir YİLDİRİM
Sude Hatun AKTİMUR
Mehmet Derya DEMİRAG
Aysu Basak OZBALCİ
Mustafa BAKİRTAS
Banu KİRTİLOGLU
Nuraydın OZLEM
Pages
2401–2413
Publication Date
2015-12-22
DOI
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Keywords: Hypercalcemia, primary hyperparathyroidism, parathyroid adenoma, parathormone, calcium

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Objective & Hypothesis:AbstractThe aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014.
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Key Findings & Data:Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study.
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Conclusion & Impact:Keywords: Hypercalcemia, primary hyperparathyroidism, parathyroid adenoma, parathormone, calcium
🔬Design:Research Article
📍Scope:2011 Verileri
⚙️Variables:Hypercalcemia · primary hyperparathyroidism · parathyroid adenoma

Abstract

AbstractThe aim of the present study was to determine the relationship between biochemical parameters, mean diameter of parathyroid adenoma (MDPA) and parathyroid hormone (PTH) levels in patients who underwent parathyroid surgery.Materials and Methods: Data were collected retrospectively from patients with hyperparathyroidism who were operated and followed in our hospital between September 2011 and April 2014. Twenty-nine (male/female = 8/21) patients with a mean age of 58.31 ± 12.59 years were enrolled into the study. The mean pre-operative serum calcium and intact PTH (iPTH) levels were 11.98±1.23 mg/dl and 386.52±374.96 pg/ml, respectively. Serum pre-operative calcium levels were found to be significantly higher in patients who had nephrolithiasis than those who did not, whereas pre-operative serum phosphate levels were lower. Pre-operative iPTH levels were found to be correlated with pre-operative calcium, alkaline phosphatase and MDPA but not with pre-operative serum phosphate. Also, pre-operative calcium levels were found to be significantly correlated with MDPA.Conclusion: Presence of nephrolithiasis is associated with higher pre-operative calcium and lower phosphate levels. Pre-operative iPTH and calcium levels were also found to be significantly correlated with MDPA; this suggests that serum iPTH and calcium levels can be useful in predicting MDPA. Keywords: Hypercalcemia, primary hyperparathyroidism, parathyroid adenoma, parathormone, calcium

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ELBUKEN, G., AKTİMUR, R., YİLDİRİM, K., AKTİMUR, S. H., DEMİRAG, M. D., OZBALCİ, A. B., BAKİRTAS, M., KİRTİLOGLU, B., OZLEM, N. (2015). Pre-opereative Parathormone Levels are Correlated with Mean Diameter of Parathyroid Adenoma and Pre-operatıve Serum Calcium and Alkaline Phosphatase Levels. Medicine Science, Cilt: 4 Sayı: 3, 2401–2413. https://ajindex.com/articles/1003230

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References (10)

  1. References Fraser WD. Hyperparathyroidism. Lancet. 2009; 374(9684):145-58.
  2. Felder EA, Kandil E. Primary hyperparathyroidism. Otolaryn Clin of North Am. 2010;43(2):417-32. Marx SJ. Hyperparathyroid and hypoparathyroid disorders. N Engl J Med. 2000;343(25);1863-75. Shane E. Clinical review 122: parathyroid carcinoma. J Clin Endocr Metab. 2001;86(2):485-93.
  3. Bandeira F, Griz L, Chaves N, Carvalho NC, Borges LM, Lazaretti-Castro M, Borba V, de Castro LC, Borges JL, Bilezikian J. Diagnosis and management of primary hyperparathyroidism--a scientific statement from the Department of Bone Metabolism, the Brazilian Society for Endocrinology and Metabolism. Arq Bras Endocrinol Metabol. 2013;57(6):406-24. Gordon W. The consequences of uncontrolled secondary hyperparathyroidism and its treatment in chronic kidney disease. Semin Dial. 2004;17(3):209-16.
  4. Bilezikian JP, Khan A, Potts Jr JT. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Third International Workshop. J Clin Endocrinol Metab. 2009;94(2):335-9.
  5. Bilezikian JP, Brandi ML, Eastell R, Silverberg SJ, Udelsman R, Marcocci C, Potts JT Jr. Guidelines for the Management of Asymptomatic Primary Hyperparathyroidism: Summary Statement from the Fourth International Workshop. J Clin Endocrinol Metab. 2014;99(10):3561-9.
  6. Silverberg SJ, Bilezikian JP. Primary hyperparathyroidism. In: Jameson JL, DeGroot LJ, senior eds, Endocrinology: Adult and Pediatric. 6th edition (online version). Philadelphia: Saunders; 2010.
  7. Schlosser K, Endres N, Celik I, Fendrich V, Rothmund M, Fernández ED. Surgical treatment of tertiary hyperparathyroidism: the choice of procedure matters! World J Surg. 2007;31(10):1947-53.
  8. Triponez F, Clark OH, Vanrenthergem Y, Evenepoel P. Surgical treatment of persistent hyperparathyroidism after renal transplantation. Ann Surg. 2008; 248(1):18-30. The American Association of Clinical Endocrinologists and the American Association of Endocrine Surgeons. Position statement on the diagnosis and management of primary hyperparathyroidism. Endocrine Practice. 2005;11(1):49-54.
  9. Marcocci C, Bollerslev J, Khan AA, Shoback DM. Medical management of primary hyperparathyroidism: Proceedings of the Fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism. J Clin Endocrinol Metab. 2014;99(10):3607-18.
  10. Bollerslev J, Marcocci C, Sosa M, Nordenström J, Bouillon R, Mosekilde L. Current evidence for recommendation of surgery, medical treatmen