Effect of Intravenously Injected Arachidonic Acid on Electrocardiography in Rats

Abstract

Arachidonic acid (AA), which is released from phospholipids in the cell membrane by a variety of stimuli, has physiological and pathophysiological roles on the cardiovascular system. The current study designed to determine the effect of intravenously (iv) injected AA on the electrocardiography (ECG) of the anesthetized rats. The ECG waves obtained from the lead II were written by placing electrodes to limbs of the ketamine and xylazine mixture (50 mg/kg/20 mg/kg; im) anesthetized adult Spraque Dawley rats. AA (3 mg/kg; iv) statistically significantly (p