Investıgatıon Of The Relatıonshıp Between P Wave Dıspersıon And Atrıal Septal Aneurysm In Pregnancy

Abstract

ABSTRACT Background: Aim of this study is to determine the impact of atrial septal aneurysm on atrial electrophysiology in pregnancy by the investigation of P-wave duration and P-wave dispersion on electrocardiography. Method: This study includes 98 pregnant women, divided in two groups according to presence of atrial septal aneurysm (ASA) (n=48 ASA positive group, n=50 ASA negative group). P-wave dispersion was calculated by using the 12-lead electrocardiogram with a speed of 50 mm/sec for each participant. Cardiac functions and morphology of the aneurysm were measured using conventional echocardiography. ASA was defined if the excursion of the septum primum into the left/right atriums exceeded 10 mm or the total excursion distance was more than 15 mm. Results: Demographic and clinical findings were similar between ASA positive group and ASA negative group, there was no significant difference. Compared to the ASA negative group, pregnant women with ASA showed significantly longer maximum P wave dispersion (PWD) (54.10±12.42 ms vs. 37,42±14,27 ms , p = 0.0001). Similarly, the maximum duration of the P wave (Pmax) in the ASA positive group was significantly longer than the ASA negative group (118,35±11,41 ms vs. 110,54±9,452 ms , p=0,0004). P wave dispersion and Pmax were not correlated with age, gravida, parity, gestational week, body mass index or M mode Echocardiographic parameters. Discussion: In this study, it was shown that P-wave dispersion is prolonged in pregnant women with atrial septal aneurysm. PWD may be a pre-determinative for atrial structural anomalies or atrial arrhythmias in pregnancy and this non invasive method should be used to predict cardiac risk at the beginning of pregnancy.