Undifferentiated pleomorphic sarcoma with focal myogenic differentiation mimicking left atrial myxoma

Abstract

Primary cardiac tumors are very rare. Cardiac sarcomas can be detected at any age, regardless of gender. At diagnosis, these are mostly symptomatic and one-third metastatic. Undifferentiated pleomorphic sarcomas account for 1.7% of all cardiac tumors, are typically localized in the left atrium, and involve the mitral valve. Here we present a case of left atrial undifferentiated pleomorphic sarcoma with myogenic differentiation that clinically and radiologically mimicked myxoma.