INVESTIGATIONS OF 44Ti PRODUCTION FOR 44Ti/44Sc RADIONUCLIDE GENERATOR

Abstract

44Sc is a promising PET radionuclide because of its short half-life of approximately 4 hours and its ability to emit positrons. In this work, a 44Ti/44Sc generator was designed to produce 44Sc. The separation and purification studies were optimized by using 46Sc as tracer. Hydroxamate and Dowex resins were used for separation process 46Sc from titanium. Briefly a 44Ti/44Sc generator system may be a source of 44Sc production in hospitals in future. If it is made suitable for hospital use, a hospital will have the opportunity to work with this generator for many years with a single production.