Two multiple sclerosis cases developed herpes zoster during use of fingolimod

Abstract

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system. Immunosuppressive and immunomodulating drugs are used during disease monitoring. Fingolimod is one of the immunomodulatory treat- ments used in MS patients. It is a therapeutic agent acting on lymphocytes. La- tent varicella-zoster virus infections may occur in MS patients receiving fingo- limod therapy. In this article, the information of two cases with varicella-zoster virus reactivation during fingolimod use were presented.