The role of paraaortic lymphadenectomy along with sentinel mapping in clinically uterine confined intermediate-high risk endometrial cancer

Abstract

Objective: This study aimed to find out whether sentinel algorithm can be sufficient in clinically uterine confined intermediate-high risk endometrial cancer. Methods: Detailed pathology characteristics and follow-up records of the 70 intermediate-high risk endometrial cancer patients were identified. Outcomes of patients who are performed sentinel algorithm and sentinel mapping followed by systematic pelvic and paraaortic lymph node dissection were compared. All patients who had obvious extrauterine disease in preoperative and intraoperative evaluation were excluded. Sentinel mapping is performed with methilene blue and cervical injection. Results: 66 patients were identified [sentinel algorithm group, 25; Paraaortic lymph node dissection group, 45]. Paraaortic lymph node dissection group had more high grade patients (p=0,02 ). The mean number of lymph nodes harvested was 11,3 and 36,9, respectively, in sentinel algorithm group and paraaortic lymph node dissection group(p