FASTING PLASMA C-PEPTIDE LEVEL PREDICTS THE RESPONSE OF GLUCAGON-LIKE PEPTIDE-1 AGONIST (EXENATIDE) ADD ON TO METFORMIN MONOTHERAPY IN OBESE TYPE 2 DIABETICS

Abstract

Fasting Plasma C-peptide Level Predicts the Response of Glucagon-like Peptide-1 Agonist (Exenatide) Addition to Metformin Monotherapy in Obese Type 2 Diabetics ABSTRACT Aim: to evaluate the predictive ability of serum C-peptide level to attain glycemic control targets by adding a glucagon-like peptide-1 receptor agonist (GLP1-RA) to metformin monotherapy in patients with type 2 diabetes and obesity. Materials and methods: This is a retrospective study, in which we enrolled 44 consecutive obese type 2 diabetic patients who were on metformin monotherapy and have inadequate glycemic control (HbA1c >7% and