Impact of Peritumoral Edema on Overall Survival in Glioblastoma Multiforme

Abstract

The aim of the present study was to investigate the relationship between peritumoral edema and overall survival in glioblastoma multiforme (GBM).METHODSTotal of 101 patients with radiologically or pathologically GBM were included in this study. Data of patient age, sex, tumor dimensions, and preoperative peritumoral edema were analyzed.RESULTSWhile average survival was 16.67±3.99 months (95% confidence interval [CI]: 8.85-24.49 months) and 1- and 3-year survival rates were 50% and 16.7%, respectively, for patients without edema, average survival was 13.74±1.95 months (95% CI: 9.91-17.58 months) and 1- and 3-year survival rates were 35.6% and 8.5%, respectively, for patients with edema. No statistical difference between them was found (p=0.297).CONCLUSIONPrognostic value of edema for survival could not be determined in this retrospective analysis of homogeneous group of patients with isolated GBM.