Incidence of type-1 retinopathy of prematurity in premature babies born small for gestational age

Özet

Amaç: Ekstrem prematüre bebeklerde ve yaşına göre uygun prematüre bebeklerde gelişmekte olan ülkede tip-1 prematüre retinopatisi (PR) insidansını incelemek. Gereç ve Yöntem: Haziran 2007-Aralık 2011 tarihleri arasında Yenidoğan Yoğunbakım Unitesinde ≤34 gestasyonel haftanın altında olup, retinal vaskularizasyonu tamamlana dek veya PR si regrese olana dek takip edilen bebekler (n=162) calışmaya dahil edildi.Tip-1-PR ETROP kriterlerine gore belirlendi. Tip-1-PR insidansı iki grupta incelendi: grup-A: ekstrem premature bebek; grup-B: yaşına uygun premature bebek. Doğum ağrlığının 10 persentilin altında olması kucuk premature bebek kriteri olarak kabul edildi. Her grupta gestasyonel yaş (GY), doğum ağırlığı (DA), herhangi bir evre PR oluşumu, tip-1-PR oluşumu, tip-1-PR oluşumunda postmenstruel hafta (PMH) incelendi. Dosyalar retrospektif tarandı. Sonuçlar: DA ve DH ortalama± grup-A da 832,45±131,74 gram, -B de 962,97±351,47gram ve 29,27±2,4 hafta ve 27,36±2,8 hafta idi. Gruplar arasında anlamlı fark bulundu (p=0,001 vs p

Abstract

Purpose: To compare the incidence of type retinopathy of prematurity (ROP) in patients small for gestational age (SGA) and in patients appropriate for gestational age (AGA) in a developing country. Material and Method: We included in this study infants (n=162) with gestational age (GA) ≤34 weeks who were screened for ROP in a neonatal intensive care unit between June 2007 and December 2011 and were followed up until the retina was completely vascularized or ROP was regressed. Type 1 ROP was defined according to the ETROP study. To describe the incidence of type 1 ROP, data were analyzed in two main groups: (A) SGA-group and (B) AGA-group. SGA was defined as birth weight below the 10th percentile for gestational age. GA in weeks, birth weight (BW) in grams (g), ROP at any stage, type 1 ROP, and post menstrual age (PMA) at type 1 ROP were evaluated for the two groups. Retrospective review of records was performed. Results: BW (in mean±SD) was 832.45±131.74 g in group A and 962.97±351.47 g in group B; GA (in mean±SD) was 29.27±2.4 weeks in group A and 27.36±2.8 weeks in group B, with significant difference between the groups (p=0.001 vs. p