Vitreomacular Interface Disorders in Behçet’s Uveitis

Abstract

Objectives: To determine the prevalence of vitreomacular interface (VMI) disorders in patients with Behçet’s uveitis and assess therelationship between VMI disorders and clinical characteristics.Materials and Methods: The macular optical coherence tomography (OCT) images of 160 eyes of 96 patients with Behçet’s uveitiswho were being followed in the Uvea-Behçet’s clinic were assessed retrospectively for VMI disorders including posterior vitreousdetachment (PVD), epiretinal membrane (ERM), vitreomacular adhesion (VMA), vitreomacular traction (VMT), full-thickness macularhole (FTMH), lamellar hole (LH) and pseudohole.Results: Twenty-four patients (25%) with unilateral and 72 patients with bilateral uveitis were included in the study. Six (30%) of 20eyes with anterior uveitis and 57 (40.7%) of 140 eyes with posterior uveitis, in total 63 (39.4%) eyes of 160 eyes had at least one VMIdisorder. PVD was detected in 4 eyes (2.5%), ERM in 48 eyes (30%), VMA in 12 eyes (7.5%), and LH in 1 eye (0.6%). None of the eyeshad VMT, FTMH, or pseudohole. ERM was detected in 13 eyes (8.1%) on fundus examination and 48 (30%) eyes by OCT (p=0.001).VMI was detected in 12 (50%) of 24 eyes with prior intraocular surgery and 51 (37.5%) of 136 eyes without. The mean duration ofuveitis was 7.3±5.8 years in patients with VMI disorders and 5.8±7.7 years in patients without (p=0.04). There was no relation betweenVMI disorders and anatomic location of uveitis, history of past ocular surgery, number of ocular/periocular steroid injections, or visualacuity.Conclusion: VMI disorders are common in patients with Behçet’s uveitis. Their frequency increases with the duration of uveitis. OCTis more sensitive than fundus examination in the detection of VMI disorders.