The Diagnostic Role of Multimodal Imaging Techniques in Isolated Foveal Hypoplasia

Abstract

To report a case of bilateral isolated foveal hypoplasia in which multimodal imaging was used to confirm the diagnosis. Fundusautofluorescence imaging, optical coherence tomography (OCT), and fundus fluorescein angiography were used to describe the typicalfindings of a patient with isolated foveal hypoplasia. Spectral domain OCT showed absence of foveal depression and persistent innerretinal layers in the fovea. Fundus autofluorescence did not reveal foveal hypoautofluorescence in the presumed foveal area. Clinicaldiagnosis of foveal hypoplasia may be difficult due to the subtle nature of fundus findings. Fundus autofluorescence imaging may helpto diagnose these patients. Foveal hypoplasia should be considered in the differential diagnosis of absence of foveal hypoautofluorescence.