Tip 2 diyabetli hastalarda epikart yağ yastıkçığı ile endotel fonksiyon bozukluğunun ilişkisi

The relationship between epicardial adipose tissue and endothelial dysfunction in patients with type 2 diabetes mellitus

İsmail Türkay ÖZCAN, Ahmet ÇELİK, Yavuz GÖZÜKARA, Emrah YEŞİL, Didem OVLA, Ahmet GÜNDEŞ, Mustafa TOPUZ

Özet

Amaç: Epikart yağ dokusu (EYD) kalp damar hastalığı riski ile ilişkilidir. Bu çalışmanın amacı tip 2 diabetes mellituslu (DM) hastalarda EYD kalınlığı ile endotel işlevlerinin ilişkisini araştırmaktır.Çalışma planı: Tip 2 DMli hastalar brakiyal arter akım aracılı dilatasyon (AAD) değerlerine göre iki gruba ayrıldı. Endotel fonksiyon bozukluğu (EFB) grubu

Abstract

Objectives: Epicardial adipose tissue (EAT) has been shown to be related to cardiovascular risk. The aim of the present study was to investigate the relationship between EAT and en- dothelial function in patients with type 2 diabetes mellitus (DM). Study design: Type 2 DM patients were divided into two groups according to their brachial flow-mediated dilatation (FMD) values. The endothelial dysfunction (ED) group con- sisted of 46 patients with FMD change of 7% were accepted as the non-ED group. EAT thickness was measured on the right ventricular free wall from the transthoracic echocardiographic paraster- nal long- and short-axis views. The patients demographic, anthropometric and laboratory findings were recorded. Results: The mean diameter of EAT was 8.0±1.8 cm in the ED group and 6.6±1.2 cm in the non-ED group (p