Eruptif Ksantomla Ortaya Çıkan Tip 2 Diabetes Mellitus ve Obeziteli Bir Ağır Hipertrigliseridemi Olgusu

A Case of Severe Hypertrigliseridemia Presentation with Eruptive Xantoma in an Adult with Type-2 Diabetes Mellitus and Obesity

Taner BAYRAKTAROĞLU, Ayşe ALPAĞUT, Rafet KOCA, Nursel DEVECİ ÇAKMAK, İhsan AYHAN

Özet

Hipertrigliseridemi, obezite ve hipotiroidizm gibi sekonder nedenler haricinde genetik lipid bozuklukları şeklinde ortaya çıkmaktadır. Farklı klinik prezantasyonları bulunmasına rağmen erişkin dönemde nadiren eruptif ksantom bulgusuyla hipertrigliseridemi olguları tanı alır. Burada, şizofreni tanısıyla izlenirken ciltte döküntüleriyle birlikte diabetes mellitus ve tip 5 hiper trigliseridemisi tanısı alan bir olguyu sunmaktayız.

Abstract

Hypertriglyceridemia occurs as genetic lipid disorders with the exception of secondary causes such as obesity and hypothyroidism. Although there are different clinical presentations, hypertriglyceridemia cases are rarely seen in adulthood with the presence of eruptive xanthoma. Here, we present a case with schizophrenia diagnosed with skin rashes and diabetes mellitus and severe hypertriglyceridemia. As seen in our case, hyperlipidemias may occur with obesity, diabetes mellitus and antipsychotics in individuals with genetic background. Their presentation may be in the form of eruptive xanthomas, a rare finding. In such cases, effective results can be obtained with a multifaceted approach to metabolic pathways without requiring lipid apheresis.

Anahtar kelimeler: Eruptif Ksantom, Hiperlipidemi, Hipertrigliseridemi, Obezite, Diabetes Mellitus, Şizofreni, antipsikotikler