THE OUTCOMES OF USING FIXED-DOSENOMOGRAM-GUIDED UNFRACTIONATEDHEPARIN THERAPY IN ELDERLY PATIENTS INCOMPARISON WITH YOUNGER PATIENTS

Abstract

Introduction: In elderly patients, the dosing of unfractionated heparin is difficult because of changing metabolism, which affects the determination of a therapeutic level. The aim of this study was to evaluate the effects of unfractionated heparin therapy in an older population and to determine whether there was any difference from a younger population in terms of the activated partial thromboplastin time results and complication rates when using a standard nomogram.Materials and Methods: A total of 120 patients aged