A case of steroid-resistance Hashimoto's encephalopathy presenting with sensorimotor polyneuropathy

Abstract

Hashimoto’s encephalopathy (HE) is a rare, auto-immune disease characterizedby symptoms of acute or subacute encephalopathy associated with increasedanti-thyroid antibody levels. The course of most HE cases is relapsing andremitting, which is similar to that of vasculitis and stroke. Steroids are thefirst line treatment in HE. In steroid non-responders other immunomodulatorytherapies or plasmapheresis could be applied. We report a case of steroidresistance HE with sensorimotor polyneuropathy, as a rare presentation ofthis disorder. Our case showed that HE may present with sensorimotorpolyneuropathy; therefore HE should be considered in the differential diagnosesof polyneuropathy.