Dergiler / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 1

The Change of Glutathione Dependent Anti-Oxidant Mechanism in Patients with Chronic Renal Disease by Hemodialysis

Sayfa
75–78
DOI
—

Özet

In order to test the for existence of a possible effect during hemodialysis we investigated glutathione and related enzymes before and after dialysis of 36 patients (20 M/16 F) with chronic renal failure (CRF). 25 healthy person (15 M/10F) served as controls. Erythrocyte reduced glutathione (GSH) concentrations, glucose -6- phosphate dehydrogenase (G-6-PD), glutathione peroxidase (GPX) activities and plasma GPX activities were significantly decreased in patients (p

Abstract

In order to test the for existence of a possible effect during hemodialysis we investigated glutathione and related enzymes before and after dialysis of 36 patients (20 M/16 F) with chronic renal failure (CRF). 25 healthy person (15 M/10F) served as controls. Erythrocyte reduced glutathione (GSH) concentrations, glucose -6- phosphate dehydrogenase (G-6-PD), glutathione peroxidase (GPX) activities and plasma GPX activities were significantly decreased in patients (p

Anahtar kelimeler: Glutathione, Glutathione peroxidase, Glucose 6-Phosphate dehydrogenase, Hemodialysis