Dergiler / Turkish Journal of Medical Sciences / 1998 / Cilt: 28 - Sayı: 5
Identification of Fibronectin Adhesins on Candida albicans
- Sayfa
- 475–480
- DOI
- —
Özet
The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.
Abstract
The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.