Neuroendocrine tumors detected in appendectomy specimens: ten-year single-center experience

Abstract

Background/aim: The aim of this study was to investigate neuroendocrine tumors (NETs) detected in appendectomy specimens andthe incidence and clinicopathologic characteristics of these tumors in our center.Materials and methods: A total of 13,863 patients were evaluated retrospectively. All underwent appendectomy operation in the KayseriTraining and Research Hospital and had a histopathological examination at the Pathology Clinic between January 2007 and March 2017.Age, sex, preoperative clinical findings, operation procedure, and histopathological examination results of the cases reported to be NETare presented.Results: NET was detected in 29 cases (0.2%) in the histopathological examination of 13,863 appendectomy specimens. Of these, 26were classical carcinoid tumors and 3 were goblet cell carcinoid tumors (GCCTs). For the NET cases, the mean age was 37 years and themale to female ratio was 1.07. Only 68.9% of the patients underwent an appendectomy, and 31% of the patients underwent a secondaryright hemicolectomy. Recurrences were not detected in any of the cases. In the present study, coincidence was determined in all of thecases with NET in the appendix.Conclusion: Contrary to many studies, both NETs of the appendix and GCCT cases were slightly higher among males and advanced agegroups in this study. The long-term life expectancy in cases of classical carcinoid tumors of the appendix is quite good.