Obstructive sleep apnea syndrome is associated with impaired pulmonary artery distensibility and right ventricular systolic dysfunction

Abstract

Background/aim: We investigated whether obstructive sleep apnea syndrome (OSAS) has any impact on pulmonary artery distensibility(PAD) and right ventricular (RV) function.Materials and methods: Subjects were categorized according to apnea–hypopnea index (AHI) as follows: controls (n = 17 and AHI 30). All subjects underwent transthoracicechocardiography after polysomnography to assess PAD and RV function. PAD was recorded as M-Mode trace of the right pulmonaryartery and was defined as (PAmax –PAmin/PAmin) × 100. S’ was measured by means of TDI of the lateral annulus of the RV using apicalfour-chamber view.Results: Patients with severe OSAS demonstrated impaired RV longitudinal systolic function (S’) compared to the other groups (P